DegronMD - O95395(GCNT3)

GCNT3

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D284N	TCGA-3N-A9WC	SKCM	TCGA	PPPY	ITCH	285:288	Mutation rewiring degron network	0.3056
p.D284N	TCGA-YD-A89C	SKCM	TCGA	PPPY	ITCH	285:288	Mutation rewiring degron network	0.3056
p.D284N	DO51234	SKCM	ICGC	PPPY	ITCH	285:288	Mutation rewiring degron network	0.3056
p.D284N	DO219501	SKCM	ICGC	PPPY	ITCH	285:288	Mutation rewiring degron network	0.3056
p.L278P	TCGA-A8-A09Z	BRCA	TCGA	PPPY	ITCH	285:288	Mutation rewiring degron network	0.1389
p.L278P	DO5521	BRCA	ICGC	PPPY	ITCH	285:288	Mutation rewiring degron network	0.1389
p.G295R	TCGA-AJ-A3EL	UCEC	TCGA	PPPY	ITCH	285:288	Mutation rewiring degron network	0.1389
p.G295R	DO41542	UCEC	ICGC	PPPY	ITCH	285:288	Mutation rewiring degron network	0.1389
p.K282N	TCGA-AP-A0LM	UCEC	TCGA	PPPY	ITCH	285:288	Mutation substituting flanking lysine	0.3611
p.K282N	DO43306	UCEC	ICGC	PPPY	ITCH	285:288	Mutation substituting flanking lysine	0.3611
p.P285H	TCGA-EA-A410	CESC	TCGA	PPPY	ITCH	285:288	Mutation altering degron motif	0.7694
p.P285H	DO49929	CESC	ICGC	PPPY	ITCH	285:288	Mutation altering degron motif	0.7694
p.P285H	ACH-001377	Pancreatic Cancer	CCLE	PPPY	ITCH	285:288	Mutation altering degron motif	0.7694
p.L278I	SIDM00002	Neuroblastoma	GDSC	PPPY	ITCH	285:288	Mutation rewiring degron network	0.1389
p.L278I	ACH-002340	Neuroblastoma	CCLE	PPPY	ITCH	285:288	Mutation rewiring degron network	0.1389
p.L278I	NBsusSR	autonomic ganglia	COSMIC	PPPY	ITCH	285:288	Mutation rewiring degron network	0.1389
p.H277L	ACH-001685	Lymphoma	CCLE	PPPY	ITCH	285:288	Mutation rewiring degron network	0.1111

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*NOTE: the Kaplan plots were collected from OncoLnc