DegronMD - O95665(NTSR2)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R253H	DO227802	COCA	ICGC	VPSTS	DEG_SPOP_SBC_1	240:244	Mutation rewiring degron network	0.0833
p.R253H	DO227802	COCA	ICGC	PGSST	DEG_SPOP_SBC_1	246:250	Mutation rewiring degron network	0.25
p.R253H	DO51491	PACA	ICGC	VPSTS	DEG_SPOP_SBC_1	240:244	Mutation rewiring degron network	0.0833
p.R253H	DO51491	PACA	ICGC	PGSST	DEG_SPOP_SBC_1	246:250	Mutation rewiring degron network	0.25
p.R253C	DO15591	HNSC	ICGC	VPSTS	DEG_SPOP_SBC_1	240:244	Mutation rewiring degron network	0.0833
p.R253C	DO15591	HNSC	ICGC	PGSST	DEG_SPOP_SBC_1	246:250	Mutation rewiring degron network	0.25
p.R253C	ACH-001378	Pancreatic Cancer	CCLE	VPSTS	DEG_SPOP_SBC_1	240:244	Mutation rewiring degron network	0.0833
p.R253C	ACH-001378	Pancreatic Cancer	CCLE	PGSST	DEG_SPOP_SBC_1	246:250	Mutation rewiring degron network	0.25
p.P241T	DO229019	LICA	ICGC	VPSTS	DEG_SPOP_SBC_1	240:244	Mutation altering degron motif	0.5919
p.A235T	DO50970	LICA	ICGC	VPSTS	DEG_SPOP_SBC_1	240:244	Mutation rewiring degron network	0.1944
p.L257P	DO35442	PACA	ICGC	PGSST	DEG_SPOP_SBC_1	246:250	Mutation rewiring degron network	0.1389
p.R253S	SIDM01133	Other Solid Cancers	GDSC	VPSTS	DEG_SPOP_SBC_1	240:244	Mutation rewiring degron network	0.0833
p.R253S	SIDM01133	Other Solid Cancers	GDSC	PGSST	DEG_SPOP_SBC_1	246:250	Mutation rewiring degron network	0.25
p.L254V	SIDM01470	Acute Myeloid Leukemia	GDSC	VPSTS	DEG_SPOP_SBC_1	240:244	Mutation rewiring degron network	0.0556
p.L254V	SIDM01470	Acute Myeloid Leukemia	GDSC	PGSST	DEG_SPOP_SBC_1	246:250	Mutation rewiring degron network	0.2222
p.L254V	ACH-000387	Leukemia	CCLE	VPSTS	DEG_SPOP_SBC_1	240:244	Mutation rewiring degron network	0.0556
p.L254V	ACH-000387	Leukemia	CCLE	PGSST	DEG_SPOP_SBC_1	246:250	Mutation rewiring degron network	0.2222

Kaplan plot for NTSR2 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

NTSR2

UniProt ID: O95665

Entrez ID: 23620

Protein name: Neurotensin receptor type 2 (NT-R-2) (NTR2) (Levocabastine-sensitive neurotensin receptor)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for NTSR2 in