FUNCTION: Epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. Participates in the regulation of epithelial migration by inhibiting the activ...
FUNCTION: Epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. Participates in the regulation of epithelial migration by inhibiting the activity of SRC during wound repair. {ECO:0000250|UniProtKB:P50446}.
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GO - Biological processes (BP):
antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell differentiation [GO:0030154]; cytolysis by host of symbiont cells [GO:0051838]; defense response to Gram-positive bacterium [GO:0050830]; morphogenesis of an epithelium [GO:0002009]; negative regulation of cyt...
antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell differentiation [GO:0030154]; cytolysis by host of symbiont cells [GO:0051838]; defense response to Gram-positive bacterium [GO:0050830]; morphogenesis of an epithelium [GO:0002009]; negative regulation of cytolysis by symbiont of host cells [GO:0001899]; negative regulation of entry of bacterium into host cell [GO:2000536]; positive regulation of cell population proliferation [GO:0008284]; wound healing [GO:0042060]
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GO - Molecular function (MF):
structural constituent of cytoskeleton [GO:0005200]...
structural constituent of cytoskeleton [GO:0005200]
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GO - Cellular component (CC):
cytosol [GO:0005829]; extracellular exosome [GO:0070062]; keratin filament [GO:0045095]; membrane [GO:0016020]; nucleus [GO:0005634]...
cytosol [GO:0005829]; extracellular exosome [GO:0070062]; keratin filament [GO:0045095]; membrane [GO:0016020]; nucleus [GO:0005634]
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