DegronMD - P04259(KRT6B)

KRT6B

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S10G	TCGA-ER-A42L	SKCM	TCGA	ASTST	DEG_SPOP_SBC_1	2:6	Mutation blocking phosphorylation signal	0.6667
p.S10G	DO223910	SKCM	ICGC	ASTST	DEG_SPOP_SBC_1	2:6	Mutation blocking phosphorylation signal	0.6667
p.R16Q	TCGA-FI-A2D5	UCEC	TCGA	ASTST	DEG_SPOP_SBC_1	2:6	Mutation rewiring degron network	0.0556
p.R16Q	DO41331	UCEC	ICGC	ASTST	DEG_SPOP_SBC_1	2:6	Mutation rewiring degron network	0.0556
p.T7I	DO229053	LICA	ICGC	ASTST	DEG_SPOP_SBC_1	2:6	Mutation rewiring degron network	0.3056
p.T6I	DO229213	THCA	ICGC	ASTST	DEG_SPOP_SBC_1	2:6	Mutation altering degron motif	0.7078

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*NOTE: the Kaplan plots were collected from OncoLnc