DegronMD - P08397(HMBS)

HMBS

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E139Q	TCGA-55-7903	LUAD	TCGA	VGTSS	DEG_SPOP_SBC_1	143:147	Mutation rewiring degron network	0.2222
p.E139Q	DO24910	LUAD	ICGC	VGTSS	DEG_SPOP_SBC_1	143:147	Mutation rewiring degron network	0.2222
p.L134I	TCGA-AM-5821	COAD	TCGA	VGTSS	DEG_SPOP_SBC_1	143:147	Mutation rewiring degron network	0.0833
p.L134I	DO8240	COAD	ICGC	VGTSS	DEG_SPOP_SBC_1	143:147	Mutation rewiring degron network	0.0833
p.S146N	TCGA-E6-A1LX	UCEC	TCGA	VGTSS	DEG_SPOP_SBC_1	143:147	Mutation altering degron motif	0.7069
p.S146N	DO41020	UCEC	ICGC	VGTSS	DEG_SPOP_SBC_1	143:147	Mutation altering degron motif	0.7069
p.R149L	DO50899	LICA	ICGC	VGTSS	DEG_SPOP_SBC_1	143:147	Mutation rewiring degron network	0.2778

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*NOTE: the Kaplan plots were collected from OncoLnc