DegronMD - P0C7U0(ELFN1)

ELFN1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E649K	DO233166	GACA	ICGC	ASTSS	DEG_SPOP_SBC_1	638:642	Mutation rewiring degron network	0.1389
p.E633K	DO233688	GACA	ICGC	ASTSS	DEG_SPOP_SBC_1	638:642	Mutation rewiring degron network	0.1944
p.Y647H	DO222405	MELA	ICGC	ASTSS	DEG_SPOP_SBC_1	638:642	Mutation rewiring degron network	0.1944
p.A641T	DO229462	SKCA	ICGC	ASTSS	DEG_SPOP_SBC_1	638:642	Mutation altering degron motif	0.7139
p.A632T	SIDM02035	Colorectal Carcinoma	GDSC	ASTSS	DEG_SPOP_SBC_1	638:642	Mutation rewiring degron network	0.1667
p.P636T	SIDM00117	Non-Small Cell Lung Carcinoma	GDSC	ASTSS	DEG_SPOP_SBC_1	638:642	Mutation rewiring degron network	0.2778
p.P636T	ACH-000837	Lung Cancer	CCLE	ASTSS	DEG_SPOP_SBC_1	638:642	Mutation rewiring degron network	0.2778
p.V630M	SIDM00032	Bladder Carcinoma	GDSC	ASTSS	DEG_SPOP_SBC_1	638:642	Mutation rewiring degron network	0.1111
p.R650L	ACH-000604	Leukemia	CCLE	ASTSS	DEG_SPOP_SBC_1	638:642	Mutation rewiring degron network	0.1111
p.P649S	ACH-001982	Metastasis	CCLE	ASTSS	DEG_SPOP_SBC_1	638:642	Mutation rewiring degron network	0.1389
p.S641L	ACH-002508	Skin Cancer	CCLE	ASTSS	DEG_SPOP_SBC_1	638:642	Mutation altering degron motif	0.7667

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*NOTE: the Kaplan plots were collected from OncoLnc