DegronMD - P11686(SFTPC)

SFTPC

Please click HERE for better display.

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R23Q	TCGA-CA-6717	COAD	TCGA	PPDY	ITCH	13:16	Mutation rewiring degron network	0.1389
p.R23Q	DO8264	COAD	ICGC	PPDY	ITCH	13:16	Mutation rewiring degron network	0.1389
p.R23Q	DO229016	COCA	ICGC	PPDY	ITCH	13:16	Mutation rewiring degron network	0.1389
p.R23Q	SIDM00547	Non-Small Cell Lung Carcinoma	GDSC	PPDY	ITCH	13:16	Mutation rewiring degron network	0.1389
p.R23Q	SIDM01618	B-Lymphoblastic Leukemia	GDSC	PPDY	ITCH	13:16	Mutation rewiring degron network	0.1389
p.P13L	TCGA-CV-5970	HNSC	TCGA	PPDY	ITCH	13:16	Mutation altering degron motif	0.7582
p.P13L	DO14280	HNSC	ICGC	PPDY	ITCH	13:16	Mutation altering degron motif	0.7582
p.S17F	TCGA-G2-AA3D	BLCA	TCGA	PPDY	ITCH	13:16	Mutation rewiring degron network	0.3056
p.S17F	DO51884	BLCA	ICGC	PPDY	ITCH	13:16	Mutation rewiring degron network	0.3056
p.A22V	DO9698	COAD	ICGC	PPDY	ITCH	13:16	Mutation rewiring degron network	0.1667
p.E17D	DO229026	LICA	ICGC	PPDY	ITCH	13:16	Mutation rewiring degron network	0.3056
p.G25V	DO229041	LICA	ICGC	PPDY	ITCH	13:16	Mutation rewiring degron network	0.0833
p.G22D	SIDM00578	Neuroblastoma	GDSC	PPDY	ITCH	13:16	Mutation rewiring degron network	0.1667
p.G25D	SIDM01117	Small Cell Lung Carcinoma	GDSC	PPDY	ITCH	13:16	Mutation rewiring degron network	0.0833
p.G25D	NCI-H748	lung	COSMIC	PPDY	ITCH	13:16	Mutation rewiring degron network	0.0833

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc