DegronMD - P14635(CCNB1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G46E	TCGA-AP-A1DK	UCEC	TCGA	PRTALGDIG	DEG_APCC_DBOX_1	41:49	Mutation altering degron motif	0.6087
p.G46E	DO42033	UCEC	ICGC	PRTALGDIG	DEG_APCC_DBOX_1	41:49	Mutation altering degron motif	0.6087
p.G46W	TCGA-D3-A1Q3	SKCM	TCGA	PRTALGDIG	DEG_APCC_DBOX_1	41:49	Mutation altering degron motif	0.6714
p.G46W	TCGA-DA-A1I5	SKCM	TCGA	PRTALGDIG	DEG_APCC_DBOX_1	41:49	Mutation altering degron motif	0.6714
p.G46W	DO37447	SKCM	ICGC	PRTALGDIG	DEG_APCC_DBOX_1	41:49	Mutation altering degron motif	0.6714
p.G46W	DO47509	SKCM	ICGC	PRTALGDIG	DEG_APCC_DBOX_1	41:49	Mutation altering degron motif	0.6714
p.P37H	TCGA-D9-A149	SKCM	TCGA	PRTALGDIG	DEG_APCC_DBOX_1	41:49	Mutation rewiring degron network	0.2222
p.P37H	DO37420	SKCM	ICGC	PRTALGDIG	DEG_APCC_DBOX_1	41:49	Mutation rewiring degron network	0.2222
p.A33S	DO229027	LICA	ICGC	PRTALGDIG	DEG_APCC_DBOX_1	41:49	Mutation rewiring degron network	0.1111
p.P31S	DO222546	MELA	ICGC	PRTALGDIG	DEG_APCC_DBOX_1	41:49	Mutation rewiring degron network	0.0556
p.D47N	SIDM00151	Ovarian Carcinoma	GDSC	PRTALGDIG	DEG_APCC_DBOX_1	41:49	Mutation altering degron motif	0.5821
p.D47N	IGROV-1	ovary	COSMIC	PRTALGDIG	DEG_APCC_DBOX_1	41:49	Mutation altering degron motif	0.5821

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons