DegronMD - P16930(FAH)

FAH

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D183E	TCGA-44-8117	LUAD	TCGA	PPVY	ITCH	187:190	Mutation rewiring degron network	0.2222
p.D183E	DO24028	LUAD	ICGC	PPVY	ITCH	187:190	Mutation rewiring degron network	0.2222
p.P182H	TCGA-AP-A059	UCEC	TCGA	PPVY	ITCH	187:190	Mutation rewiring degron network	0.1944
p.P182H	DO41361	UCEC	ICGC	PPVY	ITCH	187:190	Mutation rewiring degron network	0.1944
p.P188L	TCGA-FW-A3R5	SKCM	TCGA	PPVY	ITCH	187:190	Mutation altering degron motif	0.7582
p.P188L	DO37406	SKCM	ICGC	PPVY	ITCH	187:190	Mutation altering degron motif	0.7582
p.V189I	TCGA-G4-6628	COAD	TCGA	PPVY	ITCH	187:190	Mutation altering degron motif	0.5965
p.V189I	DO10132	COAD	ICGC	PPVY	ITCH	187:190	Mutation altering degron motif	0.5965
p.V189I	SIDM00602	Gastric Carcinoma	GDSC	PPVY	ITCH	187:190	Mutation altering degron motif	0.5965
p.V189I	SIDM00591	Oral Cavity Carcinoma	GDSC	PPVY	ITCH	187:190	Mutation altering degron motif	0.5965
p.G191C	DO229009	LICA	ICGC	PPVY	ITCH	187:190	Mutation rewiring degron network	0.3056
p.D184N	SIDM00596	Endometrial Carcinoma	GDSC	PPVY	ITCH	187:190	Mutation rewiring degron network	0.25
p.D184N	ACH-000941	Endometrial/Uterine Cancer	CCLE	PPVY	ITCH	187:190	Mutation rewiring degron network	0.25
p.D184N	ACH-000954	Endometrial/Uterine Cancer	CCLE	PPVY	ITCH	187:190	Mutation rewiring degron network	0.25
p.D184N	ACH-001517	Endometrial/Uterine Cancer	CCLE	PPVY	ITCH	187:190	Mutation rewiring degron network	0.25
p.D184N	HEC-1	endometrium	COSMIC	PPVY	ITCH	187:190	Mutation rewiring degron network	0.25

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*NOTE: the Kaplan plots were collected from OncoLnc