DegronMD - P17568(NDUFB7)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R34L	TCGA-MA-AA3Z	CESC	TCGA	PPDY	ITCH	26:29	Mutation rewiring degron network	0.1944
p.R34L	DO219722	CESC	ICGC	PPDY	ITCH	26:29	Mutation rewiring degron network	0.1944
p.G30C	DO222874	COCA	ICGC	PPDY	ITCH	26:29	Mutation rewiring degron network	0.3056
p.G30C	SIDM00425	Ovarian Carcinoma	GDSC	PPDY	ITCH	26:29	Mutation rewiring degron network	0.3056
p.G30C	SIDM00315	Glioblastoma	GDSC	PPDY	ITCH	26:29	Mutation rewiring degron network	0.3056
p.G30C	SIDM01032	Esophageal Squamous Cell Carcinoma	GDSC	PPDY	ITCH	26:29	Mutation rewiring degron network	0.3056
p.G30C	SIDM00567	Other Solid Cancers	GDSC	PPDY	ITCH	26:29	Mutation rewiring degron network	0.3056
p.G30C	SIDM00324	Neuroblastoma	GDSC	PPDY	ITCH	26:29	Mutation rewiring degron network	0.3056
p.G30C	SIDM01033	Bladder Carcinoma	GDSC	PPDY	ITCH	26:29	Mutation rewiring degron network	0.3056
p.G30C	SIDM01336	Glioblastoma	GDSC	PPDY	ITCH	26:29	Mutation rewiring degron network	0.3056
p.G30C	SIDM00171	Colorectal Carcinoma	GDSC	PPDY	ITCH	26:29	Mutation rewiring degron network	0.3056
p.G30C	KYSE-140	oesophagus	COSMIC	PPDY	ITCH	26:29	Mutation rewiring degron network	0.3056
p.G30C	YKG-1	central nervous system	COSMIC	PPDY	ITCH	26:29	Mutation rewiring degron network	0.3056
p.G30C	KU-19-19	urinary tract	COSMIC	PPDY	ITCH	26:29	Mutation rewiring degron network	0.3056
p.G30C	ONS-76	central nervous system	COSMIC	PPDY	ITCH	26:29	Mutation rewiring degron network	0.3056
p.G30C	OVTOKO	ovary	COSMIC	PPDY	ITCH	26:29	Mutation rewiring degron network	0.3056
p.G30C	HCC-56	large intestine	COSMIC	PPDY	ITCH	26:29	Mutation rewiring degron network	0.3056
p.G30C	TGW	autonomic ganglia	COSMIC	PPDY	ITCH	26:29	Mutation rewiring degron network	0.3056
p.R37L	DO50444	ESAD	ICGC	PPDY	ITCH	26:29	Mutation rewiring degron network	0.1111
p.R37S	DO229006	LICA	ICGC	PPDY	ITCH	26:29	Mutation rewiring degron network	0.1111
p.M22K	DO229234	THCA	ICGC	PPDY	ITCH	26:29	Mutation rewiring degron network	0.2222
p.E16G	DO229250	THCA	ICGC	PPDY	ITCH	26:29	Mutation rewiring degron network	0.0556
p.P27L	SIDM01951	Colorectal Carcinoma	GDSC	PPDY	ITCH	26:29	Mutation altering degron motif	0.7582

Kaplan plot for NDUFB7 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

NDUFB7

UniProt ID: P17568

Entrez ID: 4713

Protein name: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (Cell adhesion protein SQM1) (Complex I-B18) (CI-B18) (NADH-ubiquinone oxidoreductase B18 subunit)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for NDUFB7 in