DegronMD - P18827(SDC1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E101D	TCGA-EE-A183	SKCM	TCGA	AASTS	DEG_SPOP_SBC_1	87:91	Mutation rewiring degron network	0.0556
p.E101D	DO37715	SKCM	ICGC	AASTS	DEG_SPOP_SBC_1	87:91	Mutation rewiring degron network	0.0556
p.P94L	TCGA-FG-6692	LGG	TCGA	AASTS	DEG_SPOP_SBC_1	87:91	Mutation rewiring degron network	0.25
p.P94L	DO22307	LGG	ICGC	AASTS	DEG_SPOP_SBC_1	87:91	Mutation rewiring degron network	0.25
p.A95T	TCGA-VQ-A8PO	STAD	TCGA	AASTS	DEG_SPOP_SBC_1	87:91	Mutation rewiring degron network	0.2222
p.A95T	DO51773	STAD	ICGC	AASTS	DEG_SPOP_SBC_1	87:91	Mutation rewiring degron network	0.2222
p.P94T	DO229018	LICA	ICGC	AASTS	DEG_SPOP_SBC_1	87:91	Mutation rewiring degron network	0.25
p.P94T	DO229025	LICA	ICGC	AASTS	DEG_SPOP_SBC_1	87:91	Mutation rewiring degron network	0.25
p.P99T	DO229026	LICA	ICGC	AASTS	DEG_SPOP_SBC_1	87:91	Mutation rewiring degron network	0.1111
p.P99A	DO229050	LICA	ICGC	AASTS	DEG_SPOP_SBC_1	87:91	Mutation rewiring degron network	0.1111
p.G82S	SIDM00672	Hepatocellular Carcinoma	GDSC	AASTS	DEG_SPOP_SBC_1	87:91	Mutation rewiring degron network	0.1944
p.G82S	SIDM00967	Ovarian Carcinoma	GDSC	AASTS	DEG_SPOP_SBC_1	87:91	Mutation rewiring degron network	0.1944
p.G82S	SIDM00454	Rhabdomyosarcoma	GDSC	AASTS	DEG_SPOP_SBC_1	87:91	Mutation rewiring degron network	0.1944
p.G82S	SIDM01126	Small Cell Lung Carcinoma	GDSC	AASTS	DEG_SPOP_SBC_1	87:91	Mutation rewiring degron network	0.1944
p.G82S	SIDM01140	Ovarian Carcinoma	GDSC	AASTS	DEG_SPOP_SBC_1	87:91	Mutation rewiring degron network	0.1944
p.G82S	SIDM01752	Pancreatic Carcinoma	GDSC	AASTS	DEG_SPOP_SBC_1	87:91	Mutation rewiring degron network	0.1944
p.G82S	SIDM01525	Acute Myeloid Leukemia	GDSC	AASTS	DEG_SPOP_SBC_1	87:91	Mutation rewiring degron network	0.1944

Kaplan plot for SDC1 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

SDC1

UniProt ID: P18827

Entrez ID: 6382

Protein name: Syndecan-1 (SYND1) (CD antigen CD138)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for SDC1 in