DegronMD - P20783(NTF3)

NTF3

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S120R	TCGA-05-4397	LUAD	TCGA	PPLY	ITCH	115:118	Mutation rewiring degron network	0.2778
p.P115Q	TCGA-05-4410	LUAD	TCGA	PPLY	ITCH	115:118	Mutation altering degron motif	0.7035
p.S122N	TCGA-17-Z026	LUAD	TCGA	PPLY	ITCH	115:118	Mutation rewiring degron network	0.2222
p.D121E	TCGA-35-4123	LUAD	TCGA	PPLY	ITCH	115:118	Mutation rewiring degron network	0.25
p.Y112H	TCGA-37-3792	LUSC	TCGA	PPLY	ITCH	115:118	Mutation rewiring degron network	0.25
p.P115L	TCGA-B5-A0K6	UCEC	TCGA	PPLY	ITCH	115:118	Mutation altering degron motif	0.7582
p.P115L	TCGA-CM-4743	COAD	TCGA	PPLY	ITCH	115:118	Mutation altering degron motif	0.7582
p.R116W	TCGA-IB-7890	PAAD	TCGA	PPLY	ITCH	115:118	Mutation altering degron motif	0.8634
p.R111C	TCGA-NH-A8F7	COAD	TCGA	PPLY	ITCH	115:118	Mutation rewiring degron network	0.2222
p.V124M	DO223361	CLLE	ICGC	PPLY	ITCH	115:118	Mutation rewiring degron network	0.1667
p.V124M	DO233913	GACA	ICGC	PPLY	ITCH	115:118	Mutation rewiring degron network	0.1667
p.V124M	DO43907	UCEC	ICGC	PPLY	ITCH	115:118	Mutation rewiring degron network	0.1667
p.V124M	NCI-SNU-1	stomach	COSMIC	PPLY	ITCH	115:118	Mutation rewiring degron network	0.1667
p.D108E	DO26394	LUAD	ICGC	PPLY	ITCH	115:118	Mutation rewiring degron network	0.1389
p.S107R	DO25320	LUAD	ICGC	PPLY	ITCH	115:118	Mutation rewiring degron network	0.1111
p.V124L	DO52020	LUSC	ICGC	PPLY	ITCH	115:118	Mutation rewiring degron network	0.1667
p.G125R	DO31769	OV	ICGC	PPLY	ITCH	115:118	Mutation rewiring degron network	0.1389
p.Y123C	DO47925	STAD	ICGC	PPLY	ITCH	115:118	Mutation blocking phosphorylation signal	0.6389

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*NOTE: the Kaplan plots were collected from OncoLnc