DegronMD - P25025(CXCR2)

CXCR2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.H355N	TCGA-AA-3846	COAD	TCGA	VGSSS	DEG_SPOP_SBC_1	349:353	Mutation rewiring degron network	0.2778
p.H355N	DO8682	COAD	ICGC	VGSSS	DEG_SPOP_SBC_1	349:353	Mutation rewiring degron network	0.2778
p.H355N	DO229015	LICA	ICGC	VGSSS	DEG_SPOP_SBC_1	349:353	Mutation rewiring degron network	0.2778
p.S352P	DO233111	GACA	ICGC	VGSSS	DEG_SPOP_SBC_1	349:353	Mutation altering degron motif	0.7863
p.T359S	DO50969	LICA	ICGC	VGSSS	DEG_SPOP_SBC_1	349:353	Mutation rewiring degron network	0.1667
p.G354W	SIDM00643	Non-Cancerous	GDSC	VGSSS	DEG_SPOP_SBC_1	349:353	Mutation rewiring degron network	0.3056
p.G354W	ACH-000327	Lung Cancer	CCLE	VGSSS	DEG_SPOP_SBC_1	349:353	Mutation rewiring degron network	0.3056
p.G354W	ACH-002363	Non-Cancerous	CCLE	VGSSS	DEG_SPOP_SBC_1	349:353	Mutation rewiring degron network	0.3056
p.K342R	SIDM01007	T-Lymphoblastic Leukemia	GDSC	VGSSS	DEG_SPOP_SBC_1	349:353	Mutation substituting flanking lysine	0.25
p.K342R	ACH-002256	Leukemia	CCLE	VGSSS	DEG_SPOP_SBC_1	349:353	Mutation substituting flanking lysine	0.25
p.K342R	KARPAS-45	haematopoietic and lymphoid tissue	COSMIC	VGSSS	DEG_SPOP_SBC_1	349:353	Mutation substituting flanking lysine	0.25

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*NOTE: the Kaplan plots were collected from OncoLnc