DegronMD - P32238(CCKAR)

CCKAR

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G268W	TCGA-A3-3311	KIRC	TCGA	PSTTS	DEG_SPOP_SBC_1	255:259	Mutation rewiring degron network	0.0833
p.K262N	TCGA-D1-A16X	UCEC	TCGA	PSTTS	DEG_SPOP_SBC_1	255:259	Mutation substituting flanking lysine	0.3611
p.K262N	DO41799	UCEC	ICGC	PSTTS	DEG_SPOP_SBC_1	255:259	Mutation substituting flanking lysine	0.3611
p.R253K	TCGA-GN-A4U3	SKCM	TCGA	PSTTS	DEG_SPOP_SBC_1	255:259	Mutation rewiring degron network	0.2778
p.R253K	DO219484	SKCM	ICGC	PSTTS	DEG_SPOP_SBC_1	255:259	Mutation rewiring degron network	0.2778
p.K262T	TCGA-IB-7651	PAAD	TCGA	PSTTS	DEG_SPOP_SBC_1	255:259	Mutation substituting flanking lysine	0.3611
p.K262T	DO46657	PAAD	ICGC	PSTTS	DEG_SPOP_SBC_1	255:259	Mutation substituting flanking lysine	0.3611
p.C269S	TCGA-L9-A7SV	LUAD	TCGA	PSTTS	DEG_SPOP_SBC_1	255:259	Mutation rewiring degron network	0.0556
p.C269S	DO49875	LUAD	ICGC	PSTTS	DEG_SPOP_SBC_1	255:259	Mutation rewiring degron network	0.0556
p.D267N	TCGA-ZS-A9CG	LIHC	TCGA	PSTTS	DEG_SPOP_SBC_1	255:259	Mutation rewiring degron network	0.1111
p.D267N	DO52336	LIHC	ICGC	PSTTS	DEG_SPOP_SBC_1	255:259	Mutation rewiring degron network	0.1111
p.K248T	DO233168	GACA	ICGC	PSTTS	DEG_SPOP_SBC_1	255:259	Mutation substituting flanking lysine	0.25
p.G268E	DO233259	GACA	ICGC	PSTTS	DEG_SPOP_SBC_1	255:259	Mutation rewiring degron network	0.0833

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*NOTE: the Kaplan plots were collected from OncoLnc