DegronMD - P35789(ZNF93)

ZNF93

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E444K	TCGA-BT-A42C	BLCA	TCGA	VASST	DEG_SPOP_SBC_1	435:439	Mutation rewiring degron network	0.1944
p.E444K	DO49725	BLCA	ICGC	VASST	DEG_SPOP_SBC_1	435:439	Mutation rewiring degron network	0.1944
p.F434L	TCGA-CN-A63W	HNSC	TCGA	VASST	DEG_SPOP_SBC_1	435:439	Mutation rewiring degron network	0.3056
p.F434L	DO49031	HNSC	ICGC	VASST	DEG_SPOP_SBC_1	435:439	Mutation rewiring degron network	0.3056
p.K442R	DO222746	COCA	ICGC	VASST	DEG_SPOP_SBC_1	435:439	Mutation substituting flanking lysine	0.3611
p.K442R	DO222816	COCA	ICGC	VASST	DEG_SPOP_SBC_1	435:439	Mutation substituting flanking lysine	0.3611
p.K442R	DO222829	COCA	ICGC	VASST	DEG_SPOP_SBC_1	435:439	Mutation substituting flanking lysine	0.3611
p.K442R	DO51018	LAML	ICGC	VASST	DEG_SPOP_SBC_1	435:439	Mutation substituting flanking lysine	0.3611
p.K442R	DO51019	LAML	ICGC	VASST	DEG_SPOP_SBC_1	435:439	Mutation substituting flanking lysine	0.3611
p.V435I	DO222746	COCA	ICGC	VASST	DEG_SPOP_SBC_1	435:439	Mutation altering degron motif	0.7076
p.V435I	DO222829	COCA	ICGC	VASST	DEG_SPOP_SBC_1	435:439	Mutation altering degron motif	0.7076
p.C427R	DO234360	ESAD	ICGC	VASST	DEG_SPOP_SBC_1	435:439	Mutation rewiring degron network	0.1111
p.K426N	DO229141	LMS	ICGC	VASST	DEG_SPOP_SBC_1	435:439	Mutation blocking ubiquitination signal	0.5278
p.T448I	DO228785	PBCA	ICGC	VASST	DEG_SPOP_SBC_1	435:439	Mutation rewiring degron network	0.0833

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*NOTE: the Kaplan plots were collected from OncoLnc