DegronMD - P35914(HMGCL)

HMGCL

Please click HERE for better display.

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.V21I	TCGA-EE-A29V	SKCM	TCGA	AVSTS	DEG_SPOP_SBC_1	20:24	Mutation altering degron motif	0.5965
p.V21I	DO38006	SKCM	ICGC	AVSTS	DEG_SPOP_SBC_1	20:24	Mutation altering degron motif	0.5965
p.S25F	TCGA-W5-AA2Q	CHOL	TCGA	AVSTS	DEG_SPOP_SBC_1	20:24	Mutation rewiring degron network	0.3056
p.R16P	DO233262	GACA	ICGC	AVSTS	DEG_SPOP_SBC_1	20:24	Mutation rewiring degron network	0.2222
p.L15M	DO233212	GACA	ICGC	AVSTS	DEG_SPOP_SBC_1	20:24	Mutation rewiring degron network	0.1944
p.I10M	DO20790	KIRP	ICGC	AVSTS	DEG_SPOP_SBC_1	20:24	Mutation rewiring degron network	0.0556
p.N21K	DO52294	LIHC	ICGC	AVSTS	DEG_SPOP_SBC_1	20:24	Mutation altering degron motif	0.6918
p.S17F	DO222847	MELA	ICGC	AVSTS	DEG_SPOP_SBC_1	20:24	Mutation blocking phosphorylation signal	0.6944
p.R16Q	DO37259	READ	ICGC	AVSTS	DEG_SPOP_SBC_1	20:24	Mutation rewiring degron network	0.2222

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc