DegronMD - P36383(GJC1)

GJC1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P278S	TCGA-EE-A2MR	SKCM	TCGA	PPGY	ITCH	287:290	Mutation rewiring degron network	0.0833
p.P278S	DO37819	SKCM	ICGC	PPGY	ITCH	287:290	Mutation rewiring degron network	0.0833
p.Q300L	TCGA-P3-A6T6	HNSC	TCGA	PPGY	ITCH	287:290	Mutation rewiring degron network	0.0556
p.Q300L	DO49065	HNSC	ICGC	PPGY	ITCH	287:290	Mutation rewiring degron network	0.0556
p.P288L	SIDM01007	T-Lymphoblastic Leukemia	GDSC	PPGY	ITCH	287:290	Mutation altering degron motif	0.7582
p.P288L	ACH-002256	Leukemia	CCLE	PPGY	ITCH	287:290	Mutation altering degron motif	0.7582
p.P288L	KARPAS-45	haematopoietic and lymphoid tissue	COSMIC	PPGY	ITCH	287:290	Mutation altering degron motif	0.7582
p.T283I	SIDM01242	Melanoma	GDSC	PPGY	ITCH	287:290	Mutation rewiring degron network	0.2222
p.T283I	ACH-002084	Skin Cancer	CCLE	PPGY	ITCH	287:290	Mutation rewiring degron network	0.2222
p.T283I	ACH-002162	Skin Cancer	CCLE	PPGY	ITCH	287:290	Mutation rewiring degron network	0.2222
p.T283I	MMAC-SF	skin	COSMIC	PPGY	ITCH	287:290	Mutation rewiring degron network	0.2222
p.T280P	SIDM00930	Osteosarcoma	GDSC	PPGY	ITCH	287:290	Mutation rewiring degron network	0.1389
p.T280P	ACH-001715	Bone Cancer	CCLE	PPGY	ITCH	287:290	Mutation rewiring degron network	0.1389
p.T280P	CAL-72	bone	COSMIC	PPGY	ITCH	287:290	Mutation rewiring degron network	0.1389

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*NOTE: the Kaplan plots were collected from OncoLnc