DegronMD - P38432(COIL)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S248L	TCGA-BT-A20W	BLCA	TCGA	PSSSS	DEG_SPOP_SBC_1	244:248	Mutation altering degron motif	0.7667
p.S248L	DO657	BLCA	ICGC	PSSSS	DEG_SPOP_SBC_1	244:248	Mutation altering degron motif	0.7667
p.S247F	TCGA-EB-A5UM	SKCM	TCGA	PSSSS	DEG_SPOP_SBC_1	244:248	Mutation altering degron motif	0.9093
p.S247F	DO47282	SKCM	ICGC	PSSSS	DEG_SPOP_SBC_1	244:248	Mutation altering degron motif	0.9093
p.V236I	DO233270	GACA	ICGC	PSSSS	DEG_SPOP_SBC_1	244:248	Mutation rewiring degron network	0.1111
p.V236L	ACH-000975	Lung Cancer	CCLE	PSSSS	DEG_SPOP_SBC_1	244:248	Mutation rewiring degron network	0.1111

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons