DegronMD - P40305(IFI27)

IFI27

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S8L	TCGA-66-2785	LUSC	TCGA	ALTSS	DEG_SPOP_SBC_1	5:9	Mutation altering degron motif	0.8778
p.S8L	DO26520	LUSC	ICGC	ALTSS	DEG_SPOP_SBC_1	5:9	Mutation altering degron motif	0.8778
p.A10V	SIDM01016	T-Lymphoblastic Leukemia	GDSC	ALTSS	DEG_SPOP_SBC_1	5:9	Mutation rewiring degron network	0.3056
p.A10V	SIDM01263	T-Lymphoblastic Leukemia	GDSC	ALTSS	DEG_SPOP_SBC_1	5:9	Mutation rewiring degron network	0.3056
p.A10V	ACH-000995	Leukemia	CCLE	ALTSS	DEG_SPOP_SBC_1	5:9	Mutation rewiring degron network	0.3056
p.A10V	Jurkat	haematopoietic and lymphoid tissue	COSMIC	ALTSS	DEG_SPOP_SBC_1	5:9	Mutation rewiring degron network	0.3056
p.A3S	SIDM00902	Non-Small Cell Lung Carcinoma	GDSC	ALTSS	DEG_SPOP_SBC_1	5:9	Mutation rewiring degron network	0.2778
p.A3S	ACH-002337	Lung Cancer	CCLE	ALTSS	DEG_SPOP_SBC_1	5:9	Mutation rewiring degron network	0.2778
p.A5T	SIDM00150	Colorectal Carcinoma	GDSC	ALTSS	DEG_SPOP_SBC_1	5:9	Mutation altering degron motif	0.7139
p.A5T	ACH-000969	Colon/Colorectal Cancer	CCLE	ALTSS	DEG_SPOP_SBC_1	5:9	Mutation altering degron motif	0.7139
p.A5T	KM12	large intestine	COSMIC	ALTSS	DEG_SPOP_SBC_1	5:9	Mutation altering degron motif	0.7139
p.A5G	ACH-001412	Bladder Cancer	CCLE	ALTSS	DEG_SPOP_SBC_1	5:9	Mutation altering degron motif	0.754

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*NOTE: the Kaplan plots were collected from OncoLnc