DegronMD - P42696(RBM34)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R26L	TCGA-22-5479	LUSC	TCGA	DYR	CBL_MET	32:34	Mutation rewiring degron network	0.1667
p.V38I	TCGA-CN-5370	HNSC	TCGA	DYR	CBL_MET	32:34	Mutation rewiring degron network	0.2222
p.L30R	DO8264	COAD	ICGC	DYR	CBL_MET	32:34	Mutation rewiring degron network	0.2778
p.V33I	DO15126	HNSC	ICGC	DYR	CBL_MET	32:34	Mutation altering degron motif	0.7076
p.G22W	DO230556	LUSC	ICGC	DYR	CBL_MET	32:34	Mutation rewiring degron network	0.0556
p.P24T	DO222516	MELA	ICGC	DYR	CBL_MET	32:34	Mutation rewiring degron network	0.1111
p.H43N	DO47469	SKCM	ICGC	DYR	CBL_MET	32:34	Mutation rewiring degron network	0.0833
p.E41V	DO48702	SKCM	ICGC	DYR	CBL_MET	32:34	Mutation rewiring degron network	0.1389
p.H42R	DO38192	STAD	ICGC	DYR	CBL_MET	32:34	Mutation rewiring degron network	0.1111

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons