DegronMD - P43243(MATR3)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A69T	TCGA-CG-5723	STAD	TCGA	ASTSS	DEG_SPOP_SBC_1	76:80	Mutation rewiring degron network	0.1389
p.A69T	DO38376	STAD	ICGC	ASTSS	DEG_SPOP_SBC_1	76:80	Mutation rewiring degron network	0.1389
p.H70Y	TCGA-VQ-A94R	STAD	TCGA	ASTSS	DEG_SPOP_SBC_1	76:80	Mutation rewiring degron network	0.1667
p.H70Y	DO222372	STAD	ICGC	ASTSS	DEG_SPOP_SBC_1	76:80	Mutation rewiring degron network	0.1667
p.L72S	YKG-1	central nervous system	COSMIC	ASTSS	DEG_SPOP_SBC_1	76:80	Mutation rewiring degron network	0.2222
p.A76P	SN12C	kidney	COSMIC	ASTSS	DEG_SPOP_SBC_1	76:80	Mutation altering degron motif	0.6392
p.R69Q	RT-112	urinary tract	COSMIC	ASTSS	DEG_SPOP_SBC_1	76:80	Mutation rewiring degron network	0.1389
p.H90Q	TT	thyroid	COSMIC	ASTSS	DEG_SPOP_SBC_1	76:80	Mutation rewiring degron network	0.0556
p.F75L	RT4	urinary tract	COSMIC	ASTSS	DEG_SPOP_SBC_1	76:80	Mutation blocking phosphorylation signal	0.75

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons