DegronMD - P43363(MAGEA10)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.Y64C	TCGA-AJ-A3EL	UCEC	TCGA	PSSSS	DEG_SPOP_SBC_1	53:57	Mutation rewiring degron network	0.1389
p.Y64C	DO41542	UCEC	ICGC	PSSSS	DEG_SPOP_SBC_1	53:57	Mutation rewiring degron network	0.1389
p.S39L	TCGA-D3-A3MU	SKCM	TCGA	ASSST	DEG_SPOP_SBC_1	38:42	Mutation altering degron motif	0.6556
p.S39L	DO47337	SKCM	ICGC	ASSST	DEG_SPOP_SBC_1	38:42	Mutation altering degron motif	0.6556
p.S62P	TCGA-D3-A8GR	SKCM	TCGA	PSSSS	DEG_SPOP_SBC_1	53:57	Mutation rewiring degron network	0.1944
p.S62P	DO51247	SKCM	ICGC	PSSSS	DEG_SPOP_SBC_1	53:57	Mutation rewiring degron network	0.1944
p.P53S	TCGA-DA-A1I5	SKCM	TCGA	PSSSS	DEG_SPOP_SBC_1	53:57	Mutation altering degron motif	0.6752
p.P53S	TCGA-FS-A1ZA	SKCM	TCGA	PSSSS	DEG_SPOP_SBC_1	53:57	Mutation altering degron motif	0.6752
p.P53S	DO220894	MELA	ICGC	PSSSS	DEG_SPOP_SBC_1	53:57	Mutation altering degron motif	0.6752
p.P53S	DO222363	MELA	ICGC	PSSSS	DEG_SPOP_SBC_1	53:57	Mutation altering degron motif	0.6752
p.P53S	DO222653	MELA	ICGC	PSSSS	DEG_SPOP_SBC_1	53:57	Mutation altering degron motif	0.6752
p.P53S	DO222702	MELA	ICGC	PSSSS	DEG_SPOP_SBC_1	53:57	Mutation altering degron motif	0.6752
p.P53S	DO222843	MELA	ICGC	PSSSS	DEG_SPOP_SBC_1	53:57	Mutation altering degron motif	0.6752
p.P53S	DO229459	SKCA	ICGC	PSSSS	DEG_SPOP_SBC_1	53:57	Mutation altering degron motif	0.6752
p.P53S	DO37551	SKCM	ICGC	PSSSS	DEG_SPOP_SBC_1	53:57	Mutation altering degron motif	0.6752
p.P53S	DO37447	SKCM	ICGC	PSSSS	DEG_SPOP_SBC_1	53:57	Mutation altering degron motif	0.6752
p.P65H	TCGA-DF-A2KU	UCEC	TCGA	PSSSS	DEG_SPOP_SBC_1	53:57	Mutation rewiring degron network	0.1111
p.P65H	DO223286	UCEC	ICGC	PSSSS	DEG_SPOP_SBC_1	53:57	Mutation rewiring degron network	0.1111
p.E35G	TCGA-DM-A1HB	COAD	TCGA	ASSST	DEG_SPOP_SBC_1	38:42	Mutation rewiring degron network	0.25
p.S40L	TCGA-EE-A2GD	SKCM	TCGA	ASSST	DEG_SPOP_SBC_1	38:42	Mutation altering degron motif	0.7667
p.S40L	TCGA-FR-A726	SKCM	TCGA	ASSST	DEG_SPOP_SBC_1	38:42	Mutation altering degron motif	0.7667
p.S40L	DO37603	SKCM	ICGC	ASSST	DEG_SPOP_SBC_1	38:42	Mutation altering degron motif	0.7667
p.S40L	DO48665	SKCM	ICGC	ASSST	DEG_SPOP_SBC_1	38:42	Mutation altering degron motif	0.7667
p.S40L	ACH-000812	Skin Cancer	CCLE	ASSST	DEG_SPOP_SBC_1	38:42	Mutation altering degron motif	0.7667
p.S40L	COLO-783	skin	COSMIC	ASSST	DEG_SPOP_SBC_1	38:42	Mutation altering degron motif	0.7667
p.S47F	TCGA-EE-A2MT	SKCM	TCGA	ASSST	DEG_SPOP_SBC_1	38:42	Mutation rewiring degron network	0.1944
p.S47F	TCGA-EE-A2MT	SKCM	TCGA	PSSSS	DEG_SPOP_SBC_1	53:57	Mutation rewiring degron network	0.1667
p.S47F	DO38051	SKCM	ICGC	ASSST	DEG_SPOP_SBC_1	38:42	Mutation rewiring degron network	0.1944
p.S47F	DO38051	SKCM	ICGC	PSSSS	DEG_SPOP_SBC_1	53:57	Mutation rewiring degron network	0.1667
p.A33V	TCGA-GN-A26C	SKCM	TCGA	ASSST	DEG_SPOP_SBC_1	38:42	Mutation rewiring degron network	0.1944
p.A33V	DO37782	SKCM	ICGC	ASSST	DEG_SPOP_SBC_1	38:42	Mutation rewiring degron network	0.1944
p.S57F	TCGA-HT-A74H	LGG	TCGA	PSSSS	DEG_SPOP_SBC_1	53:57	Mutation altering degron motif	0.9093
p.S57F	DO219815	LGG	ICGC	PSSSS	DEG_SPOP_SBC_1	53:57	Mutation altering degron motif	0.9093
p.S57F	ACH-000369	Leukemia	CCLE	PSSSS	DEG_SPOP_SBC_1	53:57	Mutation altering degron motif	0.9093
p.T44S	DO221308	AML	ICGC	ASSST	DEG_SPOP_SBC_1	38:42	Mutation rewiring degron network	0.2778
p.T44S	DO221308	AML	ICGC	PSSSS	DEG_SPOP_SBC_1	53:57	Mutation rewiring degron network	0.0833
p.S41T	DO233760	GACA	ICGC	ASSST	DEG_SPOP_SBC_1	38:42	Mutation altering degron motif	0.6005
p.S60F	DO220878	MELA	ICGC	PSSSS	DEG_SPOP_SBC_1	53:57	Mutation rewiring degron network	0.25
p.S60F	ACH-001550	Skin Cancer	CCLE	PSSSS	DEG_SPOP_SBC_1	53:57	Mutation rewiring degron network	0.25
p.S43F	DO222875	MELA	ICGC	ASSST	DEG_SPOP_SBC_1	38:42	Mutation rewiring degron network	0.3056
p.S43F	DO222875	MELA	ICGC	PSSSS	DEG_SPOP_SBC_1	53:57	Mutation rewiring degron network	0.0556
p.P53L	DO222880	MELA	ICGC	PSSSS	DEG_SPOP_SBC_1	53:57	Mutation altering degron motif	0.7582
p.S46Y	DO232761	PBCA	ICGC	ASSST	DEG_SPOP_SBC_1	38:42	Mutation rewiring degron network	0.2222
p.S46Y	DO232761	PBCA	ICGC	PSSSS	DEG_SPOP_SBC_1	53:57	Mutation rewiring degron network	0.1389
p.P65S	DO218850	SKCA	ICGC	PSSSS	DEG_SPOP_SBC_1	53:57	Mutation rewiring degron network	0.1111
p.S54P	ACH-002026	Endometrial/Uterine Cancer	CCLE	PSSSS	DEG_SPOP_SBC_1	53:57	Mutation altering degron motif	0.5641

DegronMD: protein-targeted degradation, mutation and drug response to degrons

MAGEA10

UniProt ID: P43363

Entrez ID: 4109

Protein name: Melanoma-associated antigen 10 (Cancer/testis antigen 1.10) (CT1.10) (MAGE-10 antigen)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for MAGEA10 in