DegronMD - P43365(MAGEA12)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.T49S	TCGA-33-AAS8	LUSC	TCGA	ASSSS	DEG_SPOP_SBC_1	39:43	Mutation rewiring degron network	0.1667
p.T49S	DO219123	LUSC	ICGC	ASSSS	DEG_SPOP_SBC_1	39:43	Mutation rewiring degron network	0.1667
p.E52D	TCGA-34-5234	LUSC	TCGA	ASSSS	DEG_SPOP_SBC_1	39:43	Mutation rewiring degron network	0.0833
p.E52D	DO26810	LUSC	ICGC	ASSSS	DEG_SPOP_SBC_1	39:43	Mutation rewiring degron network	0.0833
p.S43A	TCGA-91-6829	LUAD	TCGA	ASSSS	DEG_SPOP_SBC_1	39:43	Mutation altering degron motif	0.7588
p.S43A	DO23564	LUAD	ICGC	ASSSS	DEG_SPOP_SBC_1	39:43	Mutation altering degron motif	0.7588
p.E35D	TCGA-AA-3979	COAD	TCGA	ASSSS	DEG_SPOP_SBC_1	39:43	Mutation rewiring degron network	0.2222
p.E35D	DO8586	COAD	ICGC	ASSSS	DEG_SPOP_SBC_1	39:43	Mutation rewiring degron network	0.2222
p.Q29L	TCGA-CM-5344	COAD	TCGA	ASSSS	DEG_SPOP_SBC_1	39:43	Mutation rewiring degron network	0.0556
p.Q29L	DO10252	COAD	ICGC	ASSSS	DEG_SPOP_SBC_1	39:43	Mutation rewiring degron network	0.0556
p.A30D	TCGA-D1-A16F	UCEC	TCGA	ASSSS	DEG_SPOP_SBC_1	39:43	Mutation rewiring degron network	0.0833
p.A30D	DO42408	UCEC	ICGC	ASSSS	DEG_SPOP_SBC_1	39:43	Mutation rewiring degron network	0.0833
p.R51Q	TCGA-DK-AA75	BLCA	TCGA	ASSSS	DEG_SPOP_SBC_1	39:43	Mutation rewiring degron network	0.1111
p.R51Q	DO219012	BLCA	ICGC	ASSSS	DEG_SPOP_SBC_1	39:43	Mutation rewiring degron network	0.1111
p.P31S	TCGA-FS-A1Z3	SKCM	TCGA	ASSSS	DEG_SPOP_SBC_1	39:43	Mutation rewiring degron network	0.1111
p.P31S	DO37635	SKCM	ICGC	ASSSS	DEG_SPOP_SBC_1	39:43	Mutation rewiring degron network	0.1111
p.E37K	DO220903	MELA	ICGC	ASSSS	DEG_SPOP_SBC_1	39:43	Mutation rewiring degron network	0.2778
p.Q29H	SIDM00499	Prostate Carcinoma	GDSC	ASSSS	DEG_SPOP_SBC_1	39:43	Mutation rewiring degron network	0.0556
p.Q29H	ACH-000956	Prostate Cancer	CCLE	ASSSS	DEG_SPOP_SBC_1	39:43	Mutation rewiring degron network	0.0556
p.Q29H	22RV1	prostate	COSMIC	ASSSS	DEG_SPOP_SBC_1	39:43	Mutation rewiring degron network	0.0556
p.R51G	SIDM01131	Small Cell Lung Carcinoma	GDSC	ASSSS	DEG_SPOP_SBC_1	39:43	Mutation rewiring degron network	0.1111
p.R51L	SIDM01677	Non-Small Cell Lung Carcinoma	GDSC	ASSSS	DEG_SPOP_SBC_1	39:43	Mutation rewiring degron network	0.1111
p.R51L	ACH-000845	Lung Cancer	CCLE	ASSSS	DEG_SPOP_SBC_1	39:43	Mutation rewiring degron network	0.1111

Kaplan plot for MAGEA12 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

MAGEA12

UniProt ID: P43365

Entrez ID: 4111

Protein name: Melanoma-associated antigen 12 (Cancer/testis antigen 1.12) (CT1.12) (MAGE-12 antigen) (MAGE12F antigen)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for MAGEA12 in