DegronMD - P45880(VDAC2)

VDAC2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.Y18C	DO224817	COCA	ICGC	PPSY	ITCH	15:18	Mutation altering degron motif	0.8198
p.Y18C	DO37936	SKCM	ICGC	PPSY	ITCH	15:18	Mutation altering degron motif	0.8198
p.M12V	DO234229	ESAD	ICGC	PPSY	ITCH	15:18	Mutation rewiring degron network	0.25
p.P16S	DO234232	ESAD	ICGC	PPSY	ITCH	15:18	Mutation altering degron motif	0.6752
p.S23I	DO228986	LICA	ICGC	PPSY	ITCH	15:18	Mutation blocking ubiquitination signal	0.6389
p.G18V	DO229036	LICA	ICGC	PPSY	ITCH	15:18	Mutation altering degron motif	0.7532
p.A24S	DO229045	LICA	ICGC	PPSY	ITCH	15:18	Mutation rewiring degron network	0.1667
p.R10L	DO23180	LINC	ICGC	PPSY	ITCH	15:18	Mutation rewiring degron network	0.1944
p.R8S	DO38380	STAD	ICGC	PPSY	ITCH	15:18	Mutation rewiring degron network	0.1389
p.H15Y	SIDM00294	Small Cell Lung Carcinoma	GDSC	PPSY	ITCH	15:18	Mutation altering degron motif	0.7229
p.H15Y	SIDM00498	Colorectal Carcinoma	GDSC	PPSY	ITCH	15:18	Mutation altering degron motif	0.7229
p.H15Y	SNU-C5	large intestine	COSMIC	PPSY	ITCH	15:18	Mutation altering degron motif	0.7229
p.H15Y	LU-135	lung	COSMIC	PPSY	ITCH	15:18	Mutation altering degron motif	0.7229
p.E22Q	SIDM00381	Cervical Carcinoma	GDSC	PPSY	ITCH	15:18	Mutation rewiring degron network	0.2222
p.E22Q	SKG-IIIa	cervix	COSMIC	PPSY	ITCH	15:18	Mutation rewiring degron network	0.2222

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*NOTE: the Kaplan plots were collected from OncoLnc