DegronMD - P49356(FNTB)

FNTB

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S6F	TCGA-AC-A8OQ	BRCA	TCGA	PPSSS	DEG_SPOP_SBC_1	12:16	Mutation blocking phosphorylation signal	0.6111
p.S6F	DO50034	BRCA	ICGC	PPSSS	DEG_SPOP_SBC_1	12:16	Mutation blocking phosphorylation signal	0.6111
p.P13S	TCGA-DQ-7592	HNSC	TCGA	PPSSS	DEG_SPOP_SBC_1	12:16	Mutation altering degron motif	0.5641
p.P13S	DO14157	HNSC	ICGC	PPSSS	DEG_SPOP_SBC_1	12:16	Mutation altering degron motif	0.5641
p.R13Q	DO3215	BRCA	ICGC	PPSSS	DEG_SPOP_SBC_1	12:16	Mutation altering degron motif	0.7329
p.V6A	DO233903	GACA	ICGC	PPSSS	DEG_SPOP_SBC_1	12:16	Mutation blocking phosphorylation signal	0.6111
p.V18F	DO229026	LICA	ICGC	PPSSS	DEG_SPOP_SBC_1	12:16	Mutation rewiring degron network	0.2778
p.S15A	DO232042	ORCA	ICGC	PPSSS	DEG_SPOP_SBC_1	12:16	Mutation altering degron motif	0.7588
p.S6Y	ACH-001685	Lymphoma	CCLE	PPSSS	DEG_SPOP_SBC_1	12:16	Mutation blocking phosphorylation signal	0.6111

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*NOTE: the Kaplan plots were collected from OncoLnc