DegronMD - P49765(VEGFB)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.T169A	TCGA-D1-A103	UCEC	TCGA	APSTT	DEG_SPOP_SBC_1	179:183	Mutation rewiring degron network	0.0556
p.T169A	DO42312	UCEC	ICGC	APSTT	DEG_SPOP_SBC_1	179:183	Mutation rewiring degron network	0.0556
p.T187P	TCGA-DU-8164	LGG	TCGA	APSTT	DEG_SPOP_SBC_1	179:183	Mutation rewiring degron network	0.2222
p.P170S	TCGA-EE-A3AF	SKCM	TCGA	APSTT	DEG_SPOP_SBC_1	179:183	Mutation rewiring degron network	0.0833
p.P170S	DO37911	SKCM	ICGC	APSTT	DEG_SPOP_SBC_1	179:183	Mutation rewiring degron network	0.0833
p.A176G	TCGA-KQ-A41P	BLCA	TCGA	APSTT	DEG_SPOP_SBC_1	179:183	Mutation rewiring degron network	0.25
p.P172S	TCGA-Z2-A8RT	SKCM	TCGA	APSTT	DEG_SPOP_SBC_1	179:183	Mutation rewiring degron network	0.1389
p.P172S	DO51301	SKCM	ICGC	APSTT	DEG_SPOP_SBC_1	179:183	Mutation rewiring degron network	0.1389
p.D179E	DO233947	GACA	ICGC	APSTT	DEG_SPOP_SBC_1	179:183	Mutation altering degron motif	0.6758
p.E175D	DO27835	MALY	ICGC	APSTT	DEG_SPOP_SBC_1	179:183	Mutation rewiring degron network	0.2222
p.R187Q	DO43907	UCEC	ICGC	APSTT	DEG_SPOP_SBC_1	179:183	Mutation rewiring degron network	0.2222
p.A171T	SIDM02050	Colorectal Carcinoma	GDSC	APSTT	DEG_SPOP_SBC_1	179:183	Mutation rewiring degron network	0.1111
p.A171G	SIDM00747	Non-Small Cell Lung Carcinoma	GDSC	APSTT	DEG_SPOP_SBC_1	179:183	Mutation rewiring degron network	0.1111
p.A171G	NCI-H1623	lung	COSMIC	APSTT	DEG_SPOP_SBC_1	179:183	Mutation rewiring degron network	0.1111
p.R172W	ACH-000412	Colon/Colorectal Cancer	CCLE	APSTT	DEG_SPOP_SBC_1	179:183	Mutation rewiring degron network	0.1389
p.R184Q	ACH-001498	Lymphoma	CCLE	APSTT	DEG_SPOP_SBC_1	179:183	Mutation rewiring degron network	0.3056
p.T183P	ACH-002164	Pancreatic Cancer	CCLE	APSTT	DEG_SPOP_SBC_1	179:183	Mutation altering degron motif	0.7031

Kaplan plot for VEGFB in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

VEGFB

UniProt ID: P49765

Entrez ID: 7423

Protein name: Vascular endothelial growth factor B (VEGF-B) (VEGF-related factor) (VRF)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for VEGFB in