DegronMD - P50749(RASSF2)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Data table is loading....

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R76H	TCGA-AA-3949	COAD	TCGA	PPSSS	DEG_SPOP_SBC_1	80:84	Mutation rewiring degron network	0.2222
p.R76H	TCGA-AJ-A8CV	UCEC	TCGA	PPSSS	DEG_SPOP_SBC_1	80:84	Mutation rewiring degron network	0.2222
p.R76H	TCGA-CG-5733	STAD	TCGA	PPSSS	DEG_SPOP_SBC_1	80:84	Mutation rewiring degron network	0.2222
p.R76H	DO7798	COAD	ICGC	PPSSS	DEG_SPOP_SBC_1	80:84	Mutation rewiring degron network	0.2222
p.R76H	DO38551	STAD	ICGC	PPSSS	DEG_SPOP_SBC_1	80:84	Mutation rewiring degron network	0.2222
p.R76H	DO219766	UCEC	ICGC	PPSSS	DEG_SPOP_SBC_1	80:84	Mutation rewiring degron network	0.2222
p.E75K	TCGA-AA-3984	COAD	TCGA	PPSSS	DEG_SPOP_SBC_1	80:84	Mutation rewiring degron network	0.1944
p.E75K	TCGA-EO-A22R	UCEC	TCGA	PPSSS	DEG_SPOP_SBC_1	80:84	Mutation rewiring degron network	0.1944
p.E75K	DO9002	COAD	ICGC	PPSSS	DEG_SPOP_SBC_1	80:84	Mutation rewiring degron network	0.1944
p.E75K	DO42713	UCEC	ICGC	PPSSS	DEG_SPOP_SBC_1	80:84	Mutation rewiring degron network	0.1944
p.E75K	SIDM00782	Colorectal Carcinoma	GDSC	PPSSS	DEG_SPOP_SBC_1	80:84	Mutation rewiring degron network	0.1944
p.E75K	SIDM01611	Endometrial Carcinoma	GDSC	PPSSS	DEG_SPOP_SBC_1	80:84	Mutation rewiring degron network	0.1944
p.E75K	ACH-000381	Colon/Colorectal Cancer	CCLE	PPSSS	DEG_SPOP_SBC_1	80:84	Mutation rewiring degron network	0.1944
p.E75K	ACH-000996	Endometrial/Uterine Cancer	CCLE	PPSSS	DEG_SPOP_SBC_1	80:84	Mutation rewiring degron network	0.1944
p.E75K	T84	large intestine	COSMIC	PPSSS	DEG_SPOP_SBC_1	80:84	Mutation rewiring degron network	0.1944
p.R76C	TCGA-AG-A026	READ	TCGA	PPSSS	DEG_SPOP_SBC_1	80:84	Mutation rewiring degron network	0.2222
p.R76C	DO37106	READ	ICGC	PPSSS	DEG_SPOP_SBC_1	80:84	Mutation rewiring degron network	0.2222
p.S88C	TCGA-IR-A3LK	CESC	TCGA	PPSSS	DEG_SPOP_SBC_1	80:84	Mutation rewiring degron network	0.2222
p.S88C	DO44299	CESC	ICGC	PPSSS	DEG_SPOP_SBC_1	80:84	Mutation rewiring degron network	0.2222
p.R76S	DO228986	LICA	ICGC	PPSSS	DEG_SPOP_SBC_1	80:84	Mutation rewiring degron network	0.2222
p.S85F	DO222837	MELA	ICGC	PPSSS	DEG_SPOP_SBC_1	80:84	Mutation rewiring degron network	0.3056
p.S85F	DO229446	SKCA	ICGC	PPSSS	DEG_SPOP_SBC_1	80:84	Mutation rewiring degron network	0.3056
p.P81T	DO229234	THCA	ICGC	PPSSS	DEG_SPOP_SBC_1	80:84	Mutation altering degron motif	0.5919

Kaplan plot for RASSF2 in

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

RASSF2

UniProt ID: P50749

Entrez ID: 9770

Protein name: Ras association domain-containing protein 2

External links: UniprotKB HGNC RefSeq COSMIC

Data table is loading....

Kaplan plot for RASSF2 in