DegronMD - P51965(UBE2E1)

UBE2E1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.T10A	TCGA-AP-A0LM	UCEC	TCGA	ASTSS	DEG_SPOP_SBC_1	8:12	Mutation altering degron motif	0.7139
p.T10A	DO43306	UCEC	ICGC	ASTSS	DEG_SPOP_SBC_1	8:12	Mutation altering degron motif	0.7139
p.S13Y	TCGA-ER-A19T	SKCM	TCGA	ASTSS	DEG_SPOP_SBC_1	8:12	Mutation rewiring degron network	0.3056
p.S13Y	DO51251	SKCM	ICGC	ASTSS	DEG_SPOP_SBC_1	8:12	Mutation rewiring degron network	0.3056
p.Q20K	TCGA-FS-A1ZM	SKCM	TCGA	ASTSS	DEG_SPOP_SBC_1	8:12	Mutation rewiring degron network	0.1111
p.Q20K	DO37731	SKCM	ICGC	ASTSS	DEG_SPOP_SBC_1	8:12	Mutation rewiring degron network	0.1111
p.S11N	TCGA-VQ-A8P2	STAD	TCGA	ASTSS	DEG_SPOP_SBC_1	8:12	Mutation altering degron motif	0.7069
p.S11N	DO51761	STAD	ICGC	ASTSS	DEG_SPOP_SBC_1	8:12	Mutation altering degron motif	0.7069
p.E22G	DO8018	COAD	ICGC	ASTSS	DEG_SPOP_SBC_1	8:12	Mutation rewiring degron network	0.0556
p.G15W	DO230309	COCA	ICGC	ASTSS	DEG_SPOP_SBC_1	8:12	Mutation rewiring degron network	0.25
p.R13P	DO230334	COCA	ICGC	ASTSS	DEG_SPOP_SBC_1	8:12	Mutation rewiring degron network	0.3056
p.E22D	DO228985	LICA	ICGC	ASTSS	DEG_SPOP_SBC_1	8:12	Mutation rewiring degron network	0.0556
p.K21N	DO47299	SKCM	ICGC	ASTSS	DEG_SPOP_SBC_1	8:12	Mutation rewiring degron network	0.0833

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*NOTE: the Kaplan plots were collected from OncoLnc