DegronMD - P57086(SCAND1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S39L	TCGA-AC-A23H	BRCA	TCGA	AGSSS	DEG_SPOP_SBC_1	25:29	Mutation rewiring degron network	0.0556
p.S39L	DO2401	BRCA	ICGC	AGSSS	DEG_SPOP_SBC_1	25:29	Mutation rewiring degron network	0.0556
p.E20D	TCGA-AZ-4315	COAD	TCGA	AGSSS	DEG_SPOP_SBC_1	25:29	Mutation rewiring degron network	0.1944
p.E20D	DO8842	COAD	ICGC	AGSSS	DEG_SPOP_SBC_1	25:29	Mutation rewiring degron network	0.1944
p.E20D	SIDM00118	Colorectal Carcinoma	GDSC	AGSSS	DEG_SPOP_SBC_1	25:29	Mutation rewiring degron network	0.1944
p.E20D	ACH-001081	Colon/Colorectal Cancer	CCLE	AGSSS	DEG_SPOP_SBC_1	25:29	Mutation rewiring degron network	0.1944
p.E20D	HCC2998	large intestine	COSMIC	AGSSS	DEG_SPOP_SBC_1	25:29	Mutation rewiring degron network	0.1944
p.A16E	DO229036	LICA	ICGC	AGSSS	DEG_SPOP_SBC_1	25:29	Mutation rewiring degron network	0.0833
p.C35Y	DO229257	THCA	ICGC	AGSSS	DEG_SPOP_SBC_1	25:29	Mutation rewiring degron network	0.1667
p.S28N	SIDM00407	B-Cell Non-Hodgkin's Lymphoma	GDSC	AGSSS	DEG_SPOP_SBC_1	25:29	Mutation altering degron motif	0.7069
p.S28N	ACH-000611	Lymphoma	CCLE	AGSSS	DEG_SPOP_SBC_1	25:29	Mutation altering degron motif	0.7069
p.S28N	SU-DHL-6	haematopoietic and lymphoid tissue	COSMIC	AGSSS	DEG_SPOP_SBC_1	25:29	Mutation altering degron motif	0.7069
p.P19T	SIDM00149	Melanoma	GDSC	AGSSS	DEG_SPOP_SBC_1	25:29	Mutation rewiring degron network	0.1667
p.P19T	ACH-000750	Skin Cancer	CCLE	AGSSS	DEG_SPOP_SBC_1	25:29	Mutation rewiring degron network	0.1667
p.P19T	LOXIMVI	skin	COSMIC	AGSSS	DEG_SPOP_SBC_1	25:29	Mutation rewiring degron network	0.1667
p.P31L	SIDM00451	T-Lymphoblastic Leukemia	GDSC	AGSSS	DEG_SPOP_SBC_1	25:29	Mutation rewiring degron network	0.2778
p.P31L	ACH-000937	Leukemia	CCLE	AGSSS	DEG_SPOP_SBC_1	25:29	Mutation rewiring degron network	0.2778
p.P31L	PF-382	haematopoietic and lymphoid tissue	COSMIC	AGSSS	DEG_SPOP_SBC_1	25:29	Mutation rewiring degron network	0.2778

Kaplan plot for SCAND1 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

SCAND1

UniProt ID: P57086

Entrez ID: 51282

Protein name: SCAN domain-containing protein 1

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for SCAND1 in