ERVK-25
UniProt ID: P61570
Entrez ID:
Protein name: Endogenous retrovirus group K member 25 Env polyprotein (Envelope polyprotein) (HERV-K_11q22.1 provirus ancestral Env polyprotein) [Cleaved into: Surface protein (SU); Transmembrane protein (TM)]
External links: UniprotKB HGNC RefSeq COSMIC
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FUNCTION: Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution (By similarity). {ECO:0000250}.; FUNCTION: SU mediates receptor recognition. {ECO:0000...
FUNCTION: Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution (By similarity). {ECO:0000250}.; FUNCTION: SU mediates receptor recognition. {ECO:0000250}.; FUNCTION: TM anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane with the target cell membrane (By similarity). {ECO:0000250}.
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GO - Biological processes (BP):
...
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GO - Molecular function (MF):
structural molecule activity [GO:0005198]...
structural molecule activity [GO:0005198]
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GO - Cellular component (CC):
integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]...
integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]
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ERVK-25
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Kaplan plot for ERVK-25 in
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*NOTE: the Kaplan plots were collected from OncoLnc