DegronMD - P85298(ARHGAP8)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.V17M	DO231072	LUSC	ICGC	ALSTS	DEG_SPOP_SBC_1	7:11	Mutation rewiring degron network	0.1667
p.P6H	DO37491	SKCM	ICGC	ALSTS	DEG_SPOP_SBC_1	7:11	Mutation rewiring degron network	0.3056
p.L9P	DO229213	THCA	ICGC	ALSTS	DEG_SPOP_SBC_1	7:11	Mutation altering degron motif	0.7582
p.H20Q	ACH-000919	Gastric Cancer	CCLE	ALSTS	DEG_SPOP_SBC_1	7:11	Mutation rewiring degron network	0.0833
p.H20Q	IM-95	stomach	COSMIC	ALSTS	DEG_SPOP_SBC_1	7:11	Mutation rewiring degron network	0.0833
p.H20R	ACH-002336	Unknown	CCLE	ALSTS	DEG_SPOP_SBC_1	7:11	Mutation rewiring degron network	0.0833
p.T10M	TE-8	oesophagus	COSMIC	ALSTS	DEG_SPOP_SBC_1	7:11	Mutation altering degron motif	0.7423
p.A2V	WSU-NHL	haematopoietic and lymphoid tissue	COSMIC	ALSTS	DEG_SPOP_SBC_1	7:11	Mutation rewiring degron network	0.1944

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons