DegronMD - Q00341(HDLBP)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E33K	TCGA-AO-A0JC	BRCA	TCGA	PPTY	ITCH	37:40	Mutation rewiring degron network	0.2222
p.E33Q	TCGA-BH-A1F8	BRCA	TCGA	PPTY	ITCH	37:40	Mutation rewiring degron network	0.2222
p.P45S	TCGA-DA-A1I1	SKCM	TCGA	PPTY	ITCH	37:40	Mutation rewiring degron network	0.1944
p.E50K	DO48459	BLCA	ICGC	PPTY	ITCH	37:40	Mutation substituting flanking lysine	0.1667
p.S38R	DO36556	READ	ICGC	PPTY	ITCH	37:40	Mutation altering degron motif	0.7427
p.S39F	DO36556	READ	ICGC	PPTY	ITCH	37:40	Mutation altering degron motif	0.7982
p.S39F	DO37679	SKCM	ICGC	PPTY	ITCH	37:40	Mutation altering degron motif	0.7982
p.V40I	DO41871	UCEC	ICGC	PPTY	ITCH	37:40	Mutation altering degron motif	0.7076

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons