DegronMD - Q01970(PLCB3)

PLCB3

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D939H	TCGA-33-AAS8	LUSC	TCGA	PASTS	DEG_SPOP_SBC_1	927:931	Mutation rewiring degron network	0.1111
p.D939H	DO219123	LUSC	ICGC	PASTS	DEG_SPOP_SBC_1	927:931	Mutation rewiring degron network	0.1111
p.Q937K	DO234437	ESAD	ICGC	PASTS	DEG_SPOP_SBC_1	927:931	Mutation rewiring degron network	0.1667
p.T925P	DO229144	THCA	ICGC	PASTS	DEG_SPOP_SBC_1	927:931	Mutation rewiring degron network	0.2778
p.T925P	DO229151	THCA	ICGC	PASTS	DEG_SPOP_SBC_1	927:931	Mutation rewiring degron network	0.2778
p.P921T	DO229240	THCA	ICGC	PASTS	DEG_SPOP_SBC_1	927:931	Mutation rewiring degron network	0.1667
p.T924P	DO229245	THCA	ICGC	PASTS	DEG_SPOP_SBC_1	927:931	Mutation blocking phosphorylation signal	0.6944
p.R924H	DND-41	haematopoietic and lymphoid tissue	COSMIC	PASTS	DEG_SPOP_SBC_1	927:931	Mutation blocking phosphorylation signal	0.6944
p.G928V	HCC1569	breast	COSMIC	PASTS	DEG_SPOP_SBC_1	927:931	Mutation altering degron motif	0.7532

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*NOTE: the Kaplan plots were collected from OncoLnc