DegronMD - Q02080(MEF2B)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D210N	TCGA-BG-A222	UCEC	TCGA	PPLY	ITCH	198:201	Mutation rewiring degron network	0.0833
p.E205K	TCGA-WE-A8K6	SKCM	TCGA	PPLY	ITCH	198:201	Mutation rewiring degron network	0.2222
p.R197W	DO5221	BRCA	ICGC	PPLY	ITCH	198:201	Mutation rewiring degron network	0.3056
p.R197W	DO8786	COAD	ICGC	PPLY	ITCH	198:201	Mutation rewiring degron network	0.3056
p.T207M	DO229389	BTCA	ICGC	PPLY	ITCH	198:201	Mutation rewiring degron network	0.1667
p.T207M	NCI-H1155	lung	COSMIC	PPLY	ITCH	198:201	Mutation rewiring degron network	0.1667
p.S193N	DO234230	ESAD	ICGC	PPLY	ITCH	198:201	Mutation rewiring degron network	0.1944
p.L192F	DO219692	KIRP	ICGC	PPLY	ITCH	198:201	Mutation rewiring degron network	0.1667
p.P210T	DO229018	LICA	ICGC	PPLY	ITCH	198:201	Mutation rewiring degron network	0.0833
p.P199S	DO222599	MELA	ICGC	PPLY	ITCH	198:201	Mutation altering degron motif	0.6752
p.R210W	DO232761	PBCA	ICGC	PPLY	ITCH	198:201	Mutation rewiring degron network	0.0833
p.H193Y	DO37406	SKCM	ICGC	PPLY	ITCH	198:201	Mutation rewiring degron network	0.1944
p.E208K	DO51283	SKCM	ICGC	PPLY	ITCH	198:201	Mutation rewiring degron network	0.1389
p.A188T	DO42472	UCEC	ICGC	PPLY	ITCH	198:201	Mutation rewiring degron network	0.0556
p.A188T	ACH-002207	Skin Cancer	CCLE	PPLY	ITCH	198:201	Mutation rewiring degron network	0.0556
p.T204M	SIDM00651	Non-Small Cell Lung Carcinoma	GDSC	PPLY	ITCH	198:201	Mutation rewiring degron network	0.25
p.T204M	NCI-H1155	lung	COSMIC	PPLY	ITCH	198:201	Mutation rewiring degron network	0.25
p.G206W	SIDM00618	Hepatocellular Carcinoma	GDSC	PPLY	ITCH	198:201	Mutation rewiring degron network	0.1944
p.G206W	ACH-000620	Liver Cancer	CCLE	PPLY	ITCH	198:201	Mutation rewiring degron network	0.1944
p.G206W	JHH-1	liver	COSMIC	PPLY	ITCH	198:201	Mutation rewiring degron network	0.1944
p.G209W	JHH-1	liver	COSMIC	PPLY	ITCH	198:201	Mutation rewiring degron network	0.1111

Kaplan plot for MEF2B in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

MEF2B

UniProt ID: Q02080

Entrez ID: 100271849

Protein name: Myocyte-specific enhancer factor 2B (RSRFR2) (Serum response factor-like protein 2)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for MEF2B in