DegronMD - Q08380(LGALS3BP)

LGALS3BP

Please click HERE for better display.

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.Y458H	TCGA-BR-6452	STAD	TCGA	DYR	CBL_MET	452:454	Mutation blocking phosphorylation signal	0.6667
p.Y458H	DO38404	STAD	ICGC	DYR	CBL_MET	452:454	Mutation blocking phosphorylation signal	0.6667
p.A449D	TCGA-DX-A6YT	SARC	TCGA	DYR	CBL_MET	452:454	Mutation rewiring degron network	0.25
p.A449D	DO220007	SARC	ICGC	DYR	CBL_MET	452:454	Mutation rewiring degron network	0.25
p.F447L	DO229018	LICA	ICGC	DYR	CBL_MET	452:454	Mutation rewiring degron network	0.1944
p.F461L	DO229029	LICA	ICGC	DYR	CBL_MET	452:454	Mutation rewiring degron network	0.1389
p.Q448K	DO229041	LICA	ICGC	DYR	CBL_MET	452:454	Mutation rewiring degron network	0.2222
p.F461S	SIDM00272	Breast Carcinoma	GDSC	DYR	CBL_MET	452:454	Mutation rewiring degron network	0.1389
p.F461S	ACH-000910	Breast Cancer	CCLE	DYR	CBL_MET	452:454	Mutation rewiring degron network	0.1389
p.F461S	MDA-MB-453	breast	COSMIC	DYR	CBL_MET	452:454	Mutation rewiring degron network	0.1389

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc