DegronMD - Q12765(SCRN1)

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GO - Molecular function (MF): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A12D	DO228976	LICA	ICGC	PPSY	ITCH	5:8	Mutation rewiring degron network	0.2222
p.D4E	DO229029	LICA	ICGC	PPSY	ITCH	5:8	Mutation rewiring degron network	0.3056
p.Y8H	DO24646	LUAD	ICGC	PPSY	ITCH	5:8	Mutation altering degron motif	0.7229
p.P14S	DO222595	MELA	ICGC	PPSY	ITCH	5:8	Mutation rewiring degron network	0.1667
p.D11N	DO222731	MELA	ICGC	PPSY	ITCH	5:8	Mutation rewiring degron network	0.25
p.P15Q	DO37996	SKCM	ICGC	PPSY	ITCH	5:8	Mutation rewiring degron network	0.1389
p.P15Q	ACH-000985	Colon/Colorectal Cancer	CCLE	PPSY	ITCH	5:8	Mutation rewiring degron network	0.1389
p.P15Q	LS-411N	large intestine	COSMIC	PPSY	ITCH	5:8	Mutation rewiring degron network	0.1389
p.S7I	DO41572	UCEC	ICGC	PPSY	ITCH	5:8	Mutation altering degron motif	0.623
p.R16H	DO43899	UCEC	ICGC	PPSY	ITCH	5:8	Mutation rewiring degron network	0.1111
p.G5S	SIDM01137	Pancreatic Carcinoma	GDSC	PPSY	ITCH	5:8	Mutation altering degron motif	0.6993
p.G5S	PANC-04-03	pancreas	COSMIC	PPSY	ITCH	5:8	Mutation altering degron motif	0.6993

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons