DegronMD - Q12791(KCNMA1)

KCNMA1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S50Y	TCGA-EI-6917	READ	TCGA	ASSSS	DEG_SPOP_SBC_1	38:42	Mutation blocking phosphorylation signal	0.5556
p.S50Y	DO36881	READ	ICGC	ASSSS	DEG_SPOP_SBC_1	38:42	Mutation blocking phosphorylation signal	0.5556
p.A38T	TCGA-EO-A22U	UCEC	TCGA	ASSSS	DEG_SPOP_SBC_1	38:42	Mutation altering degron motif	0.7139
p.A38T	TCGA-WL-A834	CESC	TCGA	ASSSS	DEG_SPOP_SBC_1	38:42	Mutation altering degron motif	0.7139
p.A38T	DO51651	CESC	ICGC	ASSSS	DEG_SPOP_SBC_1	38:42	Mutation altering degron motif	0.7139
p.A38T	DO43755	UCEC	ICGC	ASSSS	DEG_SPOP_SBC_1	38:42	Mutation altering degron motif	0.7139
p.L34I	DO229035	LICA	ICGC	ASSSS	DEG_SPOP_SBC_1	38:42	Mutation rewiring degron network	0.2222
p.H30R	SIDM01039	Other Solid Cancers	GDSC	ASSSS	DEG_SPOP_SBC_1	38:42	Mutation rewiring degron network	0.1111
p.D41H	TE-4	oesophagus	COSMIC	ASSSS	DEG_SPOP_SBC_1	38:42	Mutation altering degron motif	0.7688

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*NOTE: the Kaplan plots were collected from OncoLnc