DegronMD - Q12797(ASPH)

ASPH

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G19R	DO8490	COAD	ICGC	AGSSS	DEG_SPOP_SBC_1	25:29	Mutation rewiring degron network	0.1667
p.G19R	DO227549	COCA	ICGC	AGSSS	DEG_SPOP_SBC_1	25:29	Mutation rewiring degron network	0.1667
p.V37L	DO234385	ESAD	ICGC	AGSSS	DEG_SPOP_SBC_1	25:29	Mutation substituting flanking lysine	0.2222
p.D38A	DO15959	HNSC	ICGC	AGSSS	DEG_SPOP_SBC_1	25:29	Mutation rewiring degron network	0.0833
p.A33E	DO229027	LICA	ICGC	AGSSS	DEG_SPOP_SBC_1	25:29	Mutation rewiring degron network	0.2222
p.A25E	DO229037	LICA	ICGC	AGSSS	DEG_SPOP_SBC_1	25:29	Mutation altering degron motif	0.7701
p.S15N	DO23402	LINC	ICGC	AGSSS	DEG_SPOP_SBC_1	25:29	Mutation blocking phosphorylation signal	0.5
p.L35V	DO45403	LUAD	ICGC	AGSSS	DEG_SPOP_SBC_1	25:29	Mutation rewiring degron network	0.1667
p.G31R	DO229121	THCA	ICGC	AGSSS	DEG_SPOP_SBC_1	25:29	Mutation rewiring degron network	0.2778
p.S24R	DO229272	THCA	ICGC	AGSSS	DEG_SPOP_SBC_1	25:29	Mutation blocking phosphorylation signal	0.75
p.E22K	DO41644	UCEC	ICGC	AGSSS	DEG_SPOP_SBC_1	25:29	Mutation blocking phosphorylation signal	0.6944
p.G22E	DO41572	UCEC	ICGC	AGSSS	DEG_SPOP_SBC_1	25:29	Mutation blocking phosphorylation signal	0.6944
p.Q33H	DO41488	UCEC	ICGC	AGSSS	DEG_SPOP_SBC_1	25:29	Mutation rewiring degron network	0.2222
p.S20T	SIDM00120	Prostate Carcinoma	GDSC	AGSSS	DEG_SPOP_SBC_1	25:29	Mutation blocking phosphorylation signal	0.6389
p.S20T	ACH-000979	Prostate Cancer	CCLE	AGSSS	DEG_SPOP_SBC_1	25:29	Mutation blocking phosphorylation signal	0.6389

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*NOTE: the Kaplan plots were collected from OncoLnc