DegronMD - Q13478(IL18R1)

IL18R1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.H79Y	TCGA-12-0657	GBM	TCGA	PRSSS	DEG_SPOP_SBC_1	70:74	Mutation rewiring degron network	0.1944
p.H79Y	DO13911	GBM	ICGC	PRSSS	DEG_SPOP_SBC_1	70:74	Mutation rewiring degron network	0.1944
p.S74L	TCGA-A6-6781	COAD	TCGA	PRSSS	DEG_SPOP_SBC_1	70:74	Mutation altering degron motif	0.7667
p.S74L	DO8447	COAD	ICGC	PRSSS	DEG_SPOP_SBC_1	70:74	Mutation altering degron motif	0.7667
p.S62L	TCGA-CV-6942	HNSC	TCGA	PRSSS	DEG_SPOP_SBC_1	70:74	Mutation rewiring degron network	0.1111
p.S62L	DO15951	HNSC	ICGC	PRSSS	DEG_SPOP_SBC_1	70:74	Mutation rewiring degron network	0.1111
p.R75K	TCGA-F5-6814	READ	TCGA	PRSSS	DEG_SPOP_SBC_1	70:74	Mutation rewiring degron network	0.3056
p.R75K	DO36556	READ	ICGC	PRSSS	DEG_SPOP_SBC_1	70:74	Mutation rewiring degron network	0.3056
p.R71K	DO220885	MELA	ICGC	PRSSS	DEG_SPOP_SBC_1	70:74	Mutation altering degron motif	0.6126
p.R71K	DO232761	PBCA	ICGC	PRSSS	DEG_SPOP_SBC_1	70:74	Mutation altering degron motif	0.6126
p.S74W	SIDM00512	Non-Small Cell Lung Carcinoma	GDSC	PRSSS	DEG_SPOP_SBC_1	70:74	Mutation altering degron motif	0.7874
p.S74W	ACH-000662	Lung Cancer	CCLE	PRSSS	DEG_SPOP_SBC_1	70:74	Mutation altering degron motif	0.7874
p.S74W	COR-L23	lung	COSMIC	PRSSS	DEG_SPOP_SBC_1	70:74	Mutation altering degron motif	0.7874

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*NOTE: the Kaplan plots were collected from OncoLnc