DegronMD - Q13825(AUH)

AUH

Please click HERE for better display.

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P334T	TCGA-D3-A1Q3	SKCM	TCGA	PPRY	ITCH	333:336	Mutation altering degron motif	0.7031
p.P334T	DO47509	SKCM	ICGC	PPRY	ITCH	333:336	Mutation altering degron motif	0.7031
p.R335S	TCGA-EE-A29E	SKCM	TCGA	PPRY	ITCH	333:336	Mutation altering degron motif	0.6316
p.R335H	TCGA-EO-A22R	UCEC	TCGA	PPRY	ITCH	333:336	Mutation altering degron motif	0.7133
p.R335H	TCGA-MF-A522	LUSC	TCGA	PPRY	ITCH	333:336	Mutation altering degron motif	0.7133
p.R335C	DO222798	COCA	ICGC	PPRY	ITCH	333:336	Mutation altering degron motif	0.719
p.P333H	DO229019	LICA	ICGC	PPRY	ITCH	333:336	Mutation altering degron motif	0.7694
p.R332S	SIDM01045	Endometrial Carcinoma	GDSC	PPRY	ITCH	333:336	Mutation rewiring degron network	0.3056
p.R332S	ACH-000978	Endometrial/Uterine Cancer	CCLE	PPRY	ITCH	333:336	Mutation rewiring degron network	0.3056
p.R332S	EN	endometrium	COSMIC	PPRY	ITCH	333:336	Mutation rewiring degron network	0.3056
p.R335P	SIDM00357	Small Cell Lung Carcinoma	GDSC	PPRY	ITCH	333:336	Mutation altering degron motif	0.6401
p.R335P	ACH-002193	Lung Cancer	CCLE	PPRY	ITCH	333:336	Mutation altering degron motif	0.6401
p.R335P	RERF-LC-FM	lung	COSMIC	PPRY	ITCH	333:336	Mutation altering degron motif	0.6401

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc