DegronMD - Q14186(TFDP1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G356S	TCGA-2W-A8YY	CESC	TCGA	AGSTS	DEG_SPOP_SBC_1	350:354	Mutation rewiring degron network	0.2778
p.G356S	DO223732	CESC	ICGC	AGSTS	DEG_SPOP_SBC_1	350:354	Mutation rewiring degron network	0.2778
p.G356S	DO220883	MELA	ICGC	AGSTS	DEG_SPOP_SBC_1	350:354	Mutation rewiring degron network	0.2778
p.R358M	TCGA-55-A490	LUAD	TCGA	AGSTS	DEG_SPOP_SBC_1	350:354	Mutation rewiring degron network	0.2222
p.R358M	TCGA-BH-A0RX	BRCA	TCGA	AGSTS	DEG_SPOP_SBC_1	350:354	Mutation rewiring degron network	0.2222
p.R358M	DO4866	BRCA	ICGC	AGSTS	DEG_SPOP_SBC_1	350:354	Mutation rewiring degron network	0.2222
p.R358M	DO24596	LUAD	ICGC	AGSTS	DEG_SPOP_SBC_1	350:354	Mutation rewiring degron network	0.2222
p.R358S	TCGA-55-A490	LUAD	TCGA	AGSTS	DEG_SPOP_SBC_1	350:354	Mutation rewiring degron network	0.2222
p.R358K	TCGA-BH-A203	BRCA	TCGA	AGSTS	DEG_SPOP_SBC_1	350:354	Mutation rewiring degron network	0.2222
p.R358K	DO2156	BRCA	ICGC	AGSTS	DEG_SPOP_SBC_1	350:354	Mutation rewiring degron network	0.2222
p.S360Y	TCGA-D3-A3CE	SKCM	TCGA	AGSTS	DEG_SPOP_SBC_1	350:354	Mutation rewiring degron network	0.1667
p.S360Y	DO37405	SKCM	ICGC	AGSTS	DEG_SPOP_SBC_1	350:354	Mutation rewiring degron network	0.1667
p.T349M	TCGA-OR-A5J5	ACC	TCGA	AGSTS	DEG_SPOP_SBC_1	350:354	Mutation rewiring degron network	0.3056
p.V364F	DO229038	LICA	ICGC	AGSTS	DEG_SPOP_SBC_1	350:354	Mutation rewiring degron network	0.0556
p.S352F	DO230950	LUSC	ICGC	AGSTS	DEG_SPOP_SBC_1	350:354	Mutation altering degron motif	0.7982
p.S352F	DO224638	LUSC	ICGC	AGSTS	DEG_SPOP_SBC_1	350:354	Mutation altering degron motif	0.7982
p.G356N	DO220883	MELA	ICGC	AGSTS	DEG_SPOP_SBC_1	350:354	Mutation rewiring degron network	0.2778
p.G356D	DO220883	MELA	ICGC	AGSTS	DEG_SPOP_SBC_1	350:354	Mutation rewiring degron network	0.2778

Kaplan plot for TFDP1 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

TFDP1

UniProt ID: Q14186

Entrez ID: 7027

Protein name: Transcription factor Dp-1 (DRTF1-polypeptide 1) (DRTF1) (E2F dimerization partner 1)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for TFDP1 in