DegronMD - Q14296(FASTK)

FASTK

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.T423S	TCGA-36-2544	OV	TCGA	PPGY	ITCH	425:428	Mutation rewiring degron network	0.2778
p.E415K	TCGA-49-AARQ	LUAD	TCGA	PPGY	ITCH	425:428	Mutation rewiring degron network	0.0556
p.A436T	TCGA-CH-5762	PRAD	TCGA	PPGY	ITCH	425:428	Mutation rewiring degron network	0.1111
p.L433Q	TCGA-E9-A1ND	BRCA	TCGA	PPGY	ITCH	425:428	Mutation rewiring degron network	0.1944
p.V418M	DO41572	UCEC	ICGC	PPGY	ITCH	425:428	Mutation rewiring degron network	0.1389
p.V424L	SIDM00734	Non-Small Cell Lung Carcinoma	GDSC	PPGY	ITCH	425:428	Mutation rewiring degron network	0.3056
p.V424L	ACH-000589	Lung Cancer	CCLE	PPGY	ITCH	425:428	Mutation rewiring degron network	0.3056
p.V424L	NCI-H1437	lung	COSMIC	PPGY	ITCH	425:428	Mutation rewiring degron network	0.3056
p.D421H	ACH-000923	Lymphoma	CCLE	PPGY	ITCH	425:428	Mutation rewiring degron network	0.2222
p.G435D	NB13	autonomic ganglia	COSMIC	PPGY	ITCH	425:428	Mutation rewiring degron network	0.1389

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*NOTE: the Kaplan plots were collected from OncoLnc