DegronMD - Q15007(WTAP)

WTAP

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.Q238K	TCGA-D3-A2JC	SKCM	TCGA	APSTS	DEG_SPOP_SBC_1	248:252	Mutation rewiring degron network	0.0556
p.Q238K	DO47578	SKCM	ICGC	APSTS	DEG_SPOP_SBC_1	248:252	Mutation rewiring degron network	0.0556
p.P259H	TCGA-DU-6392	LGG	TCGA	APSTS	DEG_SPOP_SBC_1	248:252	Mutation rewiring degron network	0.1389
p.P259H	DO22237	LGG	ICGC	APSTS	DEG_SPOP_SBC_1	248:252	Mutation rewiring degron network	0.1389
p.A256S	TCGA-DX-A6YV	SARC	TCGA	APSTS	DEG_SPOP_SBC_1	248:252	Mutation rewiring degron network	0.2222
p.A256S	DO220011	SARC	ICGC	APSTS	DEG_SPOP_SBC_1	248:252	Mutation rewiring degron network	0.2222
p.S257Y	TCGA-EE-A2GK	SKCM	TCGA	APSTS	DEG_SPOP_SBC_1	248:252	Mutation rewiring degron network	0.1944
p.S257Y	DO37738	SKCM	ICGC	APSTS	DEG_SPOP_SBC_1	248:252	Mutation rewiring degron network	0.1944
p.Q245K	TCGA-EM-A2CL	THCA	TCGA	APSTS	DEG_SPOP_SBC_1	248:252	Mutation rewiring degron network	0.25
p.Q245K	DO40640	THCA	ICGC	APSTS	DEG_SPOP_SBC_1	248:252	Mutation rewiring degron network	0.25
p.S244C	TCGA-P3-A6T7	HNSC	TCGA	APSTS	DEG_SPOP_SBC_1	248:252	Mutation blocking phosphorylation signal	0.6667
p.S244C	DO49033	HNSC	ICGC	APSTS	DEG_SPOP_SBC_1	248:252	Mutation blocking phosphorylation signal	0.6667
p.S250R	TCGA-RD-A8NB	STAD	TCGA	APSTS	DEG_SPOP_SBC_1	248:252	Mutation altering degron motif	0.7427
p.S250R	DO50142	STAD	ICGC	APSTS	DEG_SPOP_SBC_1	248:252	Mutation altering degron motif	0.7427
p.Q242H	DO229045	LICA	ICGC	APSTS	DEG_SPOP_SBC_1	248:252	Mutation rewiring degron network	0.1667

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*NOTE: the Kaplan plots were collected from OncoLnc