DegronMD - Q15038(DAZAP2)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A41P	TCGA-61-2018	OV	TCGA	PPAY	ITCH	39:42	Mutation altering degron motif	0.6392
p.A41P	DO29218	OV	ICGC	PPAY	ITCH	39:42	Mutation altering degron motif	0.6392
p.R47C	TCGA-BR-7851	STAD	TCGA	PPAY	ITCH	39:42	Mutation rewiring degron network	0.1944
p.R47C	SIDM02039	Colorectal Carcinoma	GDSC	PPAY	ITCH	39:42	Mutation rewiring degron network	0.1944
p.Q31E	TCGA-DK-A1A3	BLCA	TCGA	PPAY	ITCH	39:42	Mutation rewiring degron network	0.1111
p.Q31E	DO558	BLCA	ICGC	PPAY	ITCH	39:42	Mutation rewiring degron network	0.1111
p.Y42C	TCGA-L5-A8NM	ESCA	TCGA	PPAY	ITCH	39:42	Mutation altering degron motif	0.7087
p.P40L	DO51638	CESC	ICGC	PPAY	ITCH	39:42	Mutation altering degron motif	0.7582
p.P40L	DO41999	UCEC	ICGC	PPAY	ITCH	39:42	Mutation altering degron motif	0.7582
p.P40L	SIDM00946	T-Lymphoblastic Leukemia	GDSC	PPAY	ITCH	39:42	Mutation altering degron motif	0.7582
p.P40L	ACH-000981	Leukemia	CCLE	PPAY	ITCH	39:42	Mutation altering degron motif	0.7582
p.P40L	DND-41	haematopoietic and lymphoid tissue	COSMIC	PPAY	ITCH	39:42	Mutation altering degron motif	0.7582
p.R47H	DO10324	COAD	ICGC	PPAY	ITCH	39:42	Mutation rewiring degron network	0.1944
p.S42C	DO228906	LICA	ICGC	PPAY	ITCH	39:42	Mutation altering degron motif	0.7541
p.G49A	DO23663	LUAD	ICGC	PPAY	ITCH	39:42	Mutation rewiring degron network	0.1389
p.S43L	SIDM00221	Melanoma	GDSC	PPAY	ITCH	39:42	Mutation rewiring degron network	0.3056
p.S43L	ACH-002388	Skin Cancer	CCLE	PPAY	ITCH	39:42	Mutation rewiring degron network	0.3056
p.P48S	SIDM00980	Gastric Carcinoma	GDSC	PPAY	ITCH	39:42	Mutation rewiring degron network	0.1667
p.P48S	ACH-000948	Gastric Cancer	CCLE	PPAY	ITCH	39:42	Mutation rewiring degron network	0.1667
p.P48S	23132-87	stomach	COSMIC	PPAY	ITCH	39:42	Mutation rewiring degron network	0.1667
p.P51L	KYSE-50	oesophagus	COSMIC	PPAY	ITCH	39:42	Mutation rewiring degron network	0.0833
p.P51L	GOTO	autonomic ganglia	COSMIC	PPAY	ITCH	39:42	Mutation rewiring degron network	0.0833
p.P46L	OVTOKO	ovary	COSMIC	PPAY	ITCH	39:42	Mutation rewiring degron network	0.2222
p.P46L	MLMA	haematopoietic and lymphoid tissue	COSMIC	PPAY	ITCH	39:42	Mutation rewiring degron network	0.2222

Kaplan plot for DAZAP2 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

DAZAP2

UniProt ID: Q15038

Entrez ID: 9802

Protein name: DAZ-associated protein 2 (Deleted in azoospermia-associated protein 2)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for DAZAP2 in