DegronMD - Q15427(SF3B4)

SF3B4

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G384R	TCGA-13-2065	OV	TCGA	PPPY	ITCH	391:394	Mutation rewiring degron network	0.1389
p.G384R	DO30560	OV	ICGC	PPPY	ITCH	391:394	Mutation rewiring degron network	0.1389
p.R390L	TCGA-18-5592	LUSC	TCGA	PPPY	ITCH	391:394	Mutation rewiring degron network	0.3056
p.R390L	DO26432	LUSC	ICGC	PPPY	ITCH	391:394	Mutation rewiring degron network	0.3056
p.R390Q	TCGA-AJ-A3EK	UCEC	TCGA	PPPY	ITCH	391:394	Mutation rewiring degron network	0.3056
p.R390Q	DO41584	UCEC	ICGC	PPPY	ITCH	391:394	Mutation rewiring degron network	0.3056
p.P392Q	TCGA-BG-A222	UCEC	TCGA	PPPY	ITCH	391:394	Mutation altering degron motif	0.7035
p.P392Q	DO42977	UCEC	ICGC	PPPY	ITCH	391:394	Mutation altering degron motif	0.7035
p.P403L	TCGA-EE-A2GC	SKCM	TCGA	PPPY	ITCH	391:394	Mutation rewiring degron network	0.0833
p.P403L	DO222494	MELA	ICGC	PPPY	ITCH	391:394	Mutation rewiring degron network	0.0833
p.P403L	DO37839	SKCM	ICGC	PPPY	ITCH	391:394	Mutation rewiring degron network	0.0833
p.P388H	DO233935	GACA	ICGC	PPPY	ITCH	391:394	Mutation rewiring degron network	0.25
p.P403Q	DO229032	LICA	ICGC	PPPY	ITCH	391:394	Mutation rewiring degron network	0.0833
p.Y394C	ACH-000978	Endometrial/Uterine Cancer	CCLE	PPPY	ITCH	391:394	Mutation altering degron motif	0.7087

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*NOTE: the Kaplan plots were collected from OncoLnc