DegronMD - Q15814(TBCC)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P160Q	TCGA-CR-7391	HNSC	TCGA	AASST	DEG_SPOP_SBC_1	146:150	Mutation rewiring degron network	0.0556
p.P160Q	DO15198	HNSC	ICGC	AASST	DEG_SPOP_SBC_1	146:150	Mutation rewiring degron network	0.0556
p.T150A	TCGA-FI-A2D5	UCEC	TCGA	AASST	DEG_SPOP_SBC_1	146:150	Mutation altering degron motif	0.7139
p.T150A	DO41331	UCEC	ICGC	AASST	DEG_SPOP_SBC_1	146:150	Mutation altering degron motif	0.7139
p.P159S	TCGA-KL-8337	KICH	TCGA	AASST	DEG_SPOP_SBC_1	146:150	Mutation rewiring degron network	0.0833
p.P159S	DO220345	KICH	ICGC	AASST	DEG_SPOP_SBC_1	146:150	Mutation rewiring degron network	0.0833
p.A147D	DO27779	MALY	ICGC	AASST	DEG_SPOP_SBC_1	146:150	Mutation altering degron motif	0.6682
p.G157D	SIDM00875	Breast Carcinoma	GDSC	AASST	DEG_SPOP_SBC_1	146:150	Mutation rewiring degron network	0.1389
p.G157D	SIDM00257	Neuroblastoma	GDSC	AASST	DEG_SPOP_SBC_1	146:150	Mutation rewiring degron network	0.1389
p.G157D	SIDM00760	Small Cell Lung Carcinoma	GDSC	AASST	DEG_SPOP_SBC_1	146:150	Mutation rewiring degron network	0.1389

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons