DegronMD - Q16585(SGCB)

SGCB

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G280V	TCGA-21-5787	LUSC	TCGA	PSSSS	DEG_SPOP_SBC_1	269:273	Mutation rewiring degron network	0.1389
p.P269S	TCGA-AX-A2HD	UCEC	TCGA	PSSSS	DEG_SPOP_SBC_1	269:273	Mutation altering degron motif	0.6752
p.L277S	SIDM02026	Colorectal Carcinoma	GDSC	PSSSS	DEG_SPOP_SBC_1	269:273	Mutation rewiring degron network	0.2222
p.M262T	SIDM00043	Head and Neck Carcinoma	GDSC	PSSSS	DEG_SPOP_SBC_1	269:273	Mutation rewiring degron network	0.1389
p.M262T	PCI-4B	upper aerodigestive tract	COSMIC	PSSSS	DEG_SPOP_SBC_1	269:273	Mutation rewiring degron network	0.1389
p.S270I	SIDM01072	Squamous Cell Lung Carcinoma	GDSC	PSSSS	DEG_SPOP_SBC_1	269:273	Mutation altering degron motif	0.623
p.S270I	ACH-000878	Lung Cancer	CCLE	PSSSS	DEG_SPOP_SBC_1	269:273	Mutation altering degron motif	0.623
p.S270I	HCC-15	lung	COSMIC	PSSSS	DEG_SPOP_SBC_1	269:273	Mutation altering degron motif	0.623

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*NOTE: the Kaplan plots were collected from OncoLnc