DegronMD - Q17RH7(TPRXL)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R203H	TCGA-DI-A2QY	UCEC	TCGA	PRSSS	DEG_SPOP_SBC_1	203:207	Mutation altering degron motif	0.8244
p.R203H	DO42031	UCEC	ICGC	PRSSS	DEG_SPOP_SBC_1	203:207	Mutation altering degron motif	0.8244
p.S139P	ACH-001398	Kidney Cancer	CCLE	PSSSS	DEG_SPOP_SBC_1	136:140	Mutation altering degron motif	0.7863
p.P83H	DO50767	LICA	ICGC	PSSSS	DEG_SPOP_SBC_1	83:87	Mutation altering degron motif	0.7694
p.C231S	DO52700	CLLE	ICGC	PSSSS	DEG_SPOP_SBC_1	228:232	Mutation altering degron motif	0.7541
p.C231S	DO232899	PEME	ICGC	PSSSS	DEG_SPOP_SBC_1	228:232	Mutation altering degron motif	0.7541
p.S132C	DO227650	PBCA	ICGC	PSSSS	DEG_SPOP_SBC_1	129:133	Mutation altering degron motif	0.7541
p.S208R	TCGA-3B-A9HI	SARC	TCGA	PSSSS	DEG_SPOP_SBC_1	208:212	Mutation altering degron motif	0.7427
p.S208R	DO219926	SARC	ICGC	PSSSS	DEG_SPOP_SBC_1	208:212	Mutation altering degron motif	0.7427
p.S208R	ACH-001610	Brain Cancer	CCLE	PSSSS	DEG_SPOP_SBC_1	208:212	Mutation altering degron motif	0.7427
p.S223I	ACH-000463	Lung Cancer	CCLE	PSSSS	DEG_SPOP_SBC_1	223:227	Mutation altering degron motif	0.7341
p.S121T	DO228584	MALY	ICGC	PSSSS	DEG_SPOP_SBC_1	118:122	Mutation altering degron motif	0.7116
p.S157T	DO227750	PBCA	ICGC	PSSSS	DEG_SPOP_SBC_1	154:158	Mutation altering degron motif	0.7116
p.S223N	DO222973	BTCA	ICGC	PSSSS	DEG_SPOP_SBC_1	223:227	Mutation altering degron motif	0.7069
p.S129N	ACH-000954	Endometrial/Uterine Cancer	CCLE	PSSSS	DEG_SPOP_SBC_1	129:133	Mutation altering degron motif	0.7069
p.P207S	DO50463	BOCA	ICGC	PRSSS	DEG_SPOP_SBC_1	203:207	Mutation altering degron motif	0.6752
p.P207S	DO223151	ESCA	ICGC	PRSSS	DEG_SPOP_SBC_1	203:207	Mutation altering degron motif	0.6752
p.P207S	DO228819	LICA	ICGC	PRSSS	DEG_SPOP_SBC_1	203:207	Mutation altering degron motif	0.6752
p.P207S	DO23212	LINC	ICGC	PRSSS	DEG_SPOP_SBC_1	203:207	Mutation altering degron motif	0.6752
p.P207S	DO232927	PEME	ICGC	PRSSS	DEG_SPOP_SBC_1	203:207	Mutation altering degron motif	0.6752

Showing 1 to 20 of 91 entries

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DegronMD: protein-targeted degradation, mutation and drug response to degrons

TPRXL

UniProt ID: Q17RH7

Entrez ID:

Protein name: Putative protein TPRXL

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for TPRXL in