DegronMD - Q2TAL6(VWC2)

VWC2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E158D	TCGA-MN-A4N4	LUAD	TCGA	DYR	CBL_MET	149:151	Mutation rewiring degron network	0.1389
p.E158D	DO26250	LUAD	ICGC	DYR	CBL_MET	149:151	Mutation rewiring degron network	0.1389
p.P148L	DO229010	COCA	ICGC	DYR	CBL_MET	149:151	Mutation rewiring degron network	0.3056
p.P148L	DO229005	COCA	ICGC	DYR	CBL_MET	149:151	Mutation rewiring degron network	0.3056
p.P148L	DO229480	LAML	ICGC	DYR	CBL_MET	149:151	Mutation rewiring degron network	0.3056
p.P148L	DO229505	LAML	ICGC	DYR	CBL_MET	149:151	Mutation rewiring degron network	0.3056
p.E143K	DO233913	GACA	ICGC	DYR	CBL_MET	149:151	Mutation rewiring degron network	0.1667
p.K153N	DO27279	LUSC	ICGC	DYR	CBL_MET	149:151	Mutation rewiring degron network	0.2778
p.R151C	DO224719	PACA	ICGC	DYR	CBL_MET	149:151	Mutation altering degron motif	0.8301
p.R151C	ACH-001518	Endometrial/Uterine Cancer	CCLE	DYR	CBL_MET	149:151	Mutation altering degron motif	0.8301
p.Y145C	DO38663	STAD	ICGC	DYR	CBL_MET	149:151	Mutation rewiring degron network	0.2222
p.V146M	SIDM02050	Colorectal Carcinoma	GDSC	DYR	CBL_MET	149:151	Mutation rewiring degron network	0.25
p.G154D	SIDM01314	Colorectal Carcinoma	GDSC	DYR	CBL_MET	149:151	Mutation rewiring degron network	0.25
p.P148T	ACH-000900	Lung Cancer	CCLE	DYR	CBL_MET	149:151	Mutation rewiring degron network	0.3056

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*NOTE: the Kaplan plots were collected from OncoLnc