DegronMD - Q32P51(HNRNPA1L2)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R319I	TCGA-06-5416	GBM	TCGA	VSSSS	DEG_SPOP_SBC_1	307:311	Mutation rewiring degron network	0.1111
p.R319I	TCGA-IB-7651	PAAD	TCGA	VSSSS	DEG_SPOP_SBC_1	307:311	Mutation rewiring degron network	0.1111
p.R319I	DO10880	GBM	ICGC	VSSSS	DEG_SPOP_SBC_1	307:311	Mutation rewiring degron network	0.1111
p.R319I	DO46657	PAAD	ICGC	VSSSS	DEG_SPOP_SBC_1	307:311	Mutation rewiring degron network	0.1111
p.S310C	TCGA-62-A46R	LUAD	TCGA	VSSSS	DEG_SPOP_SBC_1	307:311	Mutation altering degron motif	0.7541
p.S310C	DO45355	LUAD	ICGC	VSSSS	DEG_SPOP_SBC_1	307:311	Mutation altering degron motif	0.7541
p.R318I	TCGA-A5-A1OF	UCEC	TCGA	VSSSS	DEG_SPOP_SBC_1	307:311	Mutation rewiring degron network	0.1389
p.R318I	DO42568	UCEC	ICGC	VSSSS	DEG_SPOP_SBC_1	307:311	Mutation rewiring degron network	0.1389
p.G315D	TCGA-AX-A1CE	UCEC	TCGA	VSSSS	DEG_SPOP_SBC_1	307:311	Mutation rewiring degron network	0.2222
p.G315D	DO42280	UCEC	ICGC	VSSSS	DEG_SPOP_SBC_1	307:311	Mutation rewiring degron network	0.2222
p.Q300R	DO229496	LAML	ICGC	VSSSS	DEG_SPOP_SBC_1	307:311	Mutation rewiring degron network	0.1389
p.Q300R	DO229512	LAML	ICGC	VSSSS	DEG_SPOP_SBC_1	307:311	Mutation rewiring degron network	0.1389
p.V307G	DO229512	LAML	ICGC	VSSSS	DEG_SPOP_SBC_1	307:311	Mutation altering degron motif	0.7532
p.V307G	DO229061	LICA	ICGC	VSSSS	DEG_SPOP_SBC_1	307:311	Mutation altering degron motif	0.7532
p.S311I	DO50726	ORCA	ICGC	VSSSS	DEG_SPOP_SBC_1	307:311	Mutation altering degron motif	0.7341
p.G306C	DO229232	THCA	ICGC	VSSSS	DEG_SPOP_SBC_1	307:311	Mutation rewiring degron network	0.3056
p.R318G	DO229248	THCA	ICGC	VSSSS	DEG_SPOP_SBC_1	307:311	Mutation rewiring degron network	0.1389
p.S313R	DO229242	THCA	ICGC	VSSSS	DEG_SPOP_SBC_1	307:311	Mutation rewiring degron network	0.2778

Kaplan plot for HNRNPA1L2 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

HNRNPA1L2

UniProt ID: Q32P51

Entrez ID: 144983

Protein name: Heterogeneous nuclear ribonucleoprotein A1-like 2 (hnRNP A1-like 2) (hnRNP core protein A1-like 2)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for HNRNPA1L2 in